Table 2 Correlation of NAMPT genotypes and alleles with ESCC susceptibility
From: Genetic polymorphisms of NAMPT related with susceptibility to esophageal Squamous cell carcinoma
Genotype | Cases (n = 405) | Controls (n = 405) | P a | ORa(95% CI) | ||
|---|---|---|---|---|---|---|
n | % | n | % | |||
rs61330082 | ||||||
CC | 132 | 32.59 | 66 | 16.30 | 1.00 | 1.00 |
CT | 198 | 48.89 | 216 | 53.33 | <0.01 | 0.47 (0.33-0.68) |
TT | 75 | 18.52 | 123 | 30.37 | <0.01 | 0.33 (0.22-0.50) |
C Allele | 462 | 57.04 | 348 | 42.96 | 1.00 | 1.00 |
T Allele | 348 | 42.96 | 462 | 57.04 | <0.01 | 0.48 (0.38-0.61) |
rs2505568 | ||||||
TT | 168 | 41.48 | 171 | 42.22 | 1.00 | 1.00 |
AT | 237 | 58.82 | 234 | 57.78 | 0.91 | 1.02 (0.77-1.34) |
AA | 0 | 0.00 | 0 | 0.00 | - | - |
T Allele | 573 | 70.74 | 576 | 71.11 | 1.00 | 1.00 |
A Allele | 237 | 29.26 | 234 | 28.89 | 0.92 | 1.02 (0.77-1.34) |
rs9034 | ||||||
TT | 0 | 0.00 | 0 | 0.00 | - | - |
CT | 51 | 12.59 | 36 | 8.89 | 1.00 | 1.00 |
CC | 354 | 87.41 | 369 | 91.11 | 0.09 | 0.64 (0.38-1.07) |
T Allele | 51 | 6.30 | 36 | 4.44 | 1.00 | 1.00 |
C Allele | 759 | 93.70 | 774 | 95.56 | 0.13 | 0.70 (0.45-1.10) |