Table 1 Parameters during esophageal body contractions with and without administration of acotiamide
From: Effects of acotiamide on esophageal motor function and gastroesophageal reflux in healthy volunteers
| Â | Supine position | p value | Sitting position | p value | ||
|---|---|---|---|---|---|---|
Control | Acotiamide | Control | Acotiamide | |||
Segment 1 (mmHg) | 55.4 [46.0–59.7] | 64.1 [55.0–70.8] | 0.02 | 52.8 [40.8–54.7] | 56.1 [42.8–58.0] | 0.18 |
Segment 2 (mmHg) | 81.9 [68.5–96.1] | 90.5 [72.8–93.7] | 0.33 | 65.3 [62.8–75.8] | 54.3 [49.7–71.9] | 0.04 |
Segment 3 (mmHg) | 103.9 [93.7–109.4] | 106.7 [84.4–124.5] | 0.58 | 89.9 [77.0–99.7] | 88.8 [75.4–93.5] | 0.96 |
LES pressure (mmHg) | 19.8 [18.0–25.1] | 21.9 [18.4–24.1] | 0.88 | 15.0 [11.4–21.0] | 14.3 [8.5–20.9] | 0.58 |
CFV (cm/s) | 5.7 [4.6–6.1] | 5.5 [4.5–6.5] | 0.96 | 5.0 [4.2–6.5] | 4.8 [4.4–5.4] | 0.58 |