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Table 2 Risks of first drug prescription according to first level of Anatomical Therapeutic Chemical (ATC) Classification after date of diagnosis in CD subjects compared to matched referencesa

From: Risks of hospitalization and drug consumption in children and young adults with diagnosed celiac disease and the role of maternal education: a population-based matched birth cohort study

ATC codes

Drug category

REFERENCES (n = 5366)

CD (n = 1215)

HR (95 % CI)

n

py

n

py

 

A

Alimentary tract and metabolism

537

38094

298

8054

2.55 (2.19–2.97)

B

Blood and blood forming organs

258

40354

193

8846

3.69 (3.02–4.50)

C

Cardiovascular system

102

40676

43

9511

1.77 (1.22–2.57)

D

Dermatologicals

180

40060

55

9381

1.22 (0.88–1.69)

G

Genito–urinary system and sex hormones

126

40749

38

9629

1.22 (0.83–1.79)

H

Systemic hormonal preparations. excluding sex hormones and insulins

778

37614

316

8082

2.06 (1.79–2.37)

J

Antiinfectives for systemic use

3660

17612

885

3680

1.27 (1.17–1.39)

L

Antineoplastic and immunomodulating agents

19

41350

25

9697

5.24 (2.82–9.73)

M

Musculo–skeletal system

170

40674

73

9436

1.93 (1.44–2.59)

N

Nervous system

156

40703

56

9533

1.53 (1.12–2.11)

P

Antiparasitic products. insecticides and repellents

216

40259

90

9271

2.01 (1.56–2.60)

R

Respiratory system

2059

27958

560

6004

1.33 (1.20–1.48)

S

Sensory organs

147

39939

51

9252

1.42 (1.02–1.99)

  1. Py: person-years; CD: celiac disease; HR: Hazard Ratio; CI: confidence interval
  2. Figures in bold are statistically significant results (p-value <0.05)
  3. aMatched by year of birth, gender and maternal education; analysis restricted to subjects with index date ≥1995 (because drug prescription data are available from that year)