Table 2 Univariate and multivariate analysis of prognostic factors for overall survival
Variable | 5-year overall survival (Univariate analysis) | Multivariate analysis | |||
|---|---|---|---|---|---|
% | P | P | RR | Exp | |
Sex | 0.901 | ||||
Male (n = 52) | 35.3 % | ||||
Female (n = 38) | 34.3 % | ||||
Age (years) | 0.738 | ||||
≤60 (n = 35) | 34.7 % | ||||
>60 (n = 55) | 35.2 % | ||||
Location | 0.004 | 0.039 | |||
DISTAL (n = 32) | 67.6 % | 1 | (Reference) | ||
MID/DIFFUSE (n = 58) | 30.2 % | 2.299 | 1.044-5.065 | ||
Type of procedure | 0.298 | ||||
PD/PPPD (n = 73) | 31.8 % | ||||
Bile duct resection (n = 15) | 26.7 % | ||||
Transfusion | 0.808 | ||||
No (n = 77) | 32.1 % | ||||
Yes (n = 13) | 26.7 % | ||||
Postoperative complication | 0.551 | ||||
No (n = 53) | 40.5 % | ||||
Yes (n = 37) | 33.7 % | ||||
Preoperative CA 19–9 | 0.118 | ||||
<37 (n = 30) | 60.4 % | ||||
≥37 (n = 60) | 36.4 % | ||||
Gross tumor appearance | 0.039 | ||||
Papillary (n = 17) | 55.0 % | ||||
Infiltrating (n = 73) | 34.2 % | ||||
Differentiation | 0.028 | ||||
WD (n = 18) | 71.8 % | ||||
MD/PD (n = 72) | 34.7 % | ||||
Depth of invasion | 0.104 | ||||
T1 (n = 20) | 68.8 % | ||||
T2 (n = 16) | 42.1 % | ||||
T3 (n = 54) | 34.1 % | ||||
Node metastasis | 0.001 | 0.007 | |||
No (n = 56) | 51.6 % | 1 | (Reference) | ||
Yes (n = 34) | 20.0 % | 2.381 | 1.267–4.475 | ||
Lymphovascular invasion | 0.050 | ||||
No (n = 28) | 57.2 % | ||||
Yes (n = 62) | 30.2 % | ||||
Perineural invasion | 0.003 | ||||
No (n = 26) | 68.0 % | ||||
Yes (n = 64) | 33.1 % | ||||
Adjuvant CTx | 0.432 | ||||
No (n = 59) | 39.4 % | ||||
Yes (n = 31) | 37.9 % | ||||