Table 5 Number of patients (%) with the most commonly reported adverse events in the maintenance treatment phase (≥2 % in any treatment group; safety population)
Patients [n (%)] | ||
|---|---|---|
On-demand (n = 301) | Continuous (n = 294a) | |
Flatulence | 15 (5.0) | 12 (4.1) |
Abdominal pain | 10 (3.3) | 9 (3.1) |
Diarrhea | 6 (2.0) | 9 (3.1) |
Constipation | 9 (3.0) | 5 (1.7) |
Viral infection | 12 (4.0) | 8 (2.7) |
Headache | 5 (1.7) | 7 (2.4) |
Respiratory infection | 7 (2.3) | 6 (2.0) |
Gastroenteritis | 7 (2.3) | 9 (3.1) |
Back pain | 5 (1.7) | 7 (2.4) |
Arthralgia | 2 (0.7) | 6 (2.0) |