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Table 3 Treatment data and outcome

From: First clinical experience in 14 patients treated with ADVOS: a study on feasibility, safety and efficacy of a new type of albumin dialysis

 

Treat-ment time [min] [19]

Serum bilirubin [mg/dl]

Serum creatinine [mg/dl]

Serum BUN [mg/dl]

No. of treatments

28d survival

 

Day before ADVOS

Before start of ADVOS

After ADVOS

Delta [mg/dl]

Day before ADVOS

Before start of ADVOS

After ADVOS

Delta [mg/dl]

Day before ADVOS

Before start of ADVOS

After ADVOS

Delta [mg/dl]

  

Patient

P1

745

37.4

41.1

25.4

−15.7

0.7

0.8

0.5

−0.3

59

76

28

−48

19

-

P2

800

22.8

24.0

12.8

−11.2

1.0

1.0

0.9

−0.1

26

25

14

−11

10

-

P3

730

20.8

22.3

14.1

−8.2

1.8

1.6

1.5

−0.1

21

20

18

−2

7

-

P4

770

16.3

15.9

13.2

−2.7

2.4

1.9

1.5

−0.4

27

20

18

−2

29

-

P5

800

n.d.

11.6

9.2

−2.4

n.d.

2.8

1.2

−1.6

n.d.

45

13

−32

3

-

P6

600

43.5

41.6

34.2

−7.4

3.9

3.3

2.2

−1.1

91

97

63

−34

22

+

P7

720

3.1

5.3

3.9

−1.4

1.7

3.0

2.1

−0.9

19

33

22

−11

17

+

P8

420

21.6

20.7

17.8

−2.9

1.3

2.0

2.8

+0.8

44

69

82

+13

9

-

P9

570

26.4

26.2

20.3

−5.9

1.9

2.3

1.7

−0.6

43

51

35

−16

6

+

P10

300

1.9

2.0

1.5

−0.5

1.7

1.3

0.7

−0.6

54

31

16

−15

1

-

P11

240

40.4

41.6

29.0

−12.6

3.0

3.2

2.0

−01.2

35

40

27

−13

101

+

P12

510

18.3

17.5

10.9

−6.6

1.4

2.9

2.1

−0.8

40

49

27

−22

3

-

P13

360

38.2

42.1

19.9

−22.2

3.0

2.3

1.2

−1.1

79

68

33

−35

11

+

P14

480

49.3

51.8

35.7

−16.1

3.0

3.0

2.2

−0.8

54

67

39

−28

1

-

Mean ± SD Number [%]

575± 193

26.2± 14.9

26.0± 15.4

17.7± 10.5

−8.3± 6.5

2.0± 0.9

2.2± 0.8

1.6± 0.7

−0.6± 0.6

46± 22

49± 23

31± 20

−18± 16

17± 26 [1–101]

5/14 [36%]

  1. ADVOS advanced organ support
  2. BUN blood urea nitrogen
  3. n.d. not done
  4. Delta absolute changes when comparing values immediately before and after the first ADVOS session