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Table 1 Characteristics of the study cohort (n = 576)

From: Proteinuria and baseline renal function predict mortality and renal outcomes after sirolimus therapy in liver transplantation recipients

Characteristics

Data

Age at baseline, years

53.93 ± 9.20

Sex, male, %

456 (79.17%)

Duration between LT and SRL initiation, months

15.70 ± 33.5

eGFR at baseline, ml/min/1.73 m2

78.60 ± 42.94

SCr at baseline, mg/dL

1.16 ± 0.72

Positive proteinuria at baseline (n = 535), n (%)

75 (14.02%)

Indications for liver transplantation, n (%) a

 Decompensated liver cirrhosis

  Hepatitis B

317 (55.03%)

  Hepatitis C

162 (28.13%)

  Alcoholic

87 (15.10%)

 HCC

318 (55.21%)

 Acute liver failure

34 (5.9%)

Baseline comorbidities, n (%)

 Congestive heart failure

3 (0.52%)

 Diabetes mellitus

144 (25%)

 Celebrovascular disease

5 (0.87%)

 Chronic pulmonary disease

26 (4.52%)

 Renal disease

21 (3.65%)

CNI use at baseline

520 (90.28%)

Plasma trough level of SRL, ng/mL

 <3 months,

6.19 ± 3.52

 3-6 months

6.26 ± 2.96

 6-12 months

6.19 ± 2.88

Duration of follow-up, day, (n = 574)

1075 ± 871.2

  1. Data presents as mean ± SD for continuous data, and n (%) for categorical data
  2. aNot excluding events