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Table 5 The predictive values of a range of salivary pepsin concentrations to identify patients with GERD

From: The diagnostic value of pepsin detection in saliva for gastro-esophageal reflux disease: a preliminary study from China

Concentrations (ng/mL)

Sen (%)

Spe (%)

Youden index (%)

PPV (%)

NPV (%)

PLR

NLR

≥16

85.1

47.1

32.2

60.5

76.8

1.61

0.32

≥76

73.0

88.3

61.3

85.6

77.4

6.24

0.30

≥125

54.8

90.0

44.8

83.9

67.6

5.48

0.50

≥200

44.3

97.2

41.5

93.8

64.7

15.82

0.57

  1. GERD gastro-esophageal reflux disease, Sen sensitivity, Spe specificity, PPV positive predictive value, NPV negative predictive value, PLR positive likelihood ratio, NLR negative likelihood ratio