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Table 3 Cut-off FC levels for discriminating clinical remission and mucosal healing

From: Fecal calprotectin predicts complete mucosal healing and better correlates with the ulcerative colitis endoscopic index of severity than with the Mayo endoscopic subscore in patients with ulcerative colitis

 

Cut-off FC level (mg/kg)

AUC (95% CI)

p value

Sensitivity

Specificity

pMS = 0

1272

0.748 (0.616–0.880)

<0.001

0.857

0.599

pMS = 0–2

2211

0.772 (0.701–0.842)

<0.001

0.875

0.592

MES = 0

187

0.883 (0.772–1.000)

<0.001

0.857

0.891

UCEIS = 0

187

0.883 (0.772–1.000)

<0.001

0.857

0.891

  1. pMS partial Mayo score, MES Mayo endoscopic subscore, UCEIS ulcerative colitis endoscopic index of severity, FC fecal calprotectin, AUC area under curve, CI confidence interval