Table 3 Monitoring and drugs costs (US$ and PPP-adjusted US$) for treatment of genotype-1 patient with chronic hepatitis C according to different regimens recommended by the BMoH from 2011 to 2015
| Â | PEG-RBV | PEG-RBV/BOC | PEG-RBV/TEL | SOF/DCV | SOF/SIM | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Â | US$ | PPP$ | US$ | PPP$ | US$ | PPP$ | US$ | PPP$ | US$ | PPP$ |
TE | – | – | 53.35 | 95.32 | 53.35 | 95.32 | 53.35 | 95.32 | 53.35 | 95.32 |
Liver biopsy | 482.32 | 834.41 | – | – | – | – | – | – | – | – |
Total | 482.32 | 834.41 | 53.35 | 95.32 | 53.35 | 95.32 | 53.35 | 95.32 | 53.35 | 95.32 |
Blood analysis tests | ||||||||||
 WBC. RBC and platelet | 159.39 | 286.72 | 180.64 | 324.95 | 170.02 | 305.84 | 63.76 | 114.69 | 63.76 | 114.69 |
 Fasting glucose | 29.20 | 52.52 | 29.20 | 52.52 | 29.20 | 52.52 | 29.20 | 52.52 | 29.20 | 52.52 |
 BUN/creatinine | 72.58 | 130.56 | 77.41 | 139.26 | 72.58 | 130.56 | 29.03 | 52.22 | 29.03 | 52.22 |
 ALT | 72.78 | 130.92 | 77.63 | 139.65 | 72.78 | 130.92 | 29.11 | 52.37 | 29.11 | 52.37 |
 AST | 72.91 | 131.16 | 77.78 | 139.91 | 72.91 | 131.16 | 29.17 | 52.47 | 29.17 | 52.47 |
 AP | 28.61 | 51.46 | 28.61 | 51.46 | 28.61 | 51.46 | 28.61 | 51.46 | 28.61 | 51.46 |
 GGT | 28.99 | 52.15 | 28.99 | 52.15 | 28.99 | 52.15 | 28.99 | 52.15 | 28.99 | 52.15 |
 Total bilirubin | 29.04 | 52.24 | 29.04 | 52.24 | 29.04 | 52.24 | 29.04 | 52.24 | 29.04 | 52.24 |
 Albumin | 30.44 | 54.75 | 30.44 | 54.75 | 30.44 | 54.75 | 30.44 | 54.75 | 30.44 | 54.75 |
 INR | 40.10 | 72.14 | 86.89 | 156.30 | 93.57 | 168.32 | 40.10 | 72.14 | 40.10 | 72.14 |
 HCV genotype | 156.33 | 281.22 | 156.33 | 281.22 | 156.33 | 281.22 | 156.33 | 281.22 | 156.33 | 281.22 |
 HCV-RNA | 696.43 | 1252.80 | 609.38 | 1096.20 | 609.38 | 1096.20 | 174.11 | 313.20 | 174.11 | 313.20 |
 TSH | 157.55 | 283.41 | 157.55 | 283.41 | 157.55 | 283.41 |  | – |  | – |
 Beta-hCG | 182.07 | 327.53 | 182.07 | 327.53 | 182.07 | 327.53 | 182.07 | 327.53 | 182.07 | 327.53 |
Total | 1756.41 | 3159.58 | 1751.94 | 3151.54 | 1733.45 | 3118.27 | 849.94 | 1528.95 | 849.94 | 1528.95 |
Medical follow-up | ||||||||||
 GP’s medical visit | 54.54 | 98.11 | 54.54 | 98.11 | 54.54 | 98.11 | 54.54 | 98.11 | 54.54 | 98.11 |
 Specialist’s visit | 880.95 | 1584.73 | 880.95 | 1584.73 | 880.95 | 1584.73 | 314.62 | 565.97 | 314.62 | 565.97 |
 Blood sample | 567.52 | 1020.90 | 567.52 | 1020.90 | 567.52 | 1020.90 | 227.01 | 408.36 | 227.01 | 408.36 |
 Nursing consultation | 159.15 | 286.29 | 159.15 | 286.29 | 159.15 | 286.29 | 127.32 | 229.03 | 127.32 | 229.03 |
Total | 1662.15 | 2990.02 | 1662.15 | 2990.02 | 1662.15 | 2990.02 | 723.49 | 1301.47 | 723.49 | 1301.47 |
Drugs | ||||||||||
 PEG-IFN 180 mcg | 17,290.59 | 31,103.78 | 17,290.59 | 31,103.78 | 17,290.59 | 31,103.78 | – | – | – | – |
 Ribavirin 250 mg | 2828.69 | 5088.49 | 2828.69 | 5088.49 | 2828.69 | 5088.49 | – | – | – | – |
 Boceprevir 200 mg | – | – | 15,991.51 | 28,766.88 | – | – | – | – | – | – |
 Telaprevir 375 mg | – | – | – | – | 24,378.69 | 43,854.45 | – | – | – | – |
 Sofosbuvir 400 mg | – | – | – | – | – | – | 6765.68 | 12,170.68 | 6765.68 | 12,170.68 |
 Daclastavir 60 mg | – | – | – | – | – | – | 2593.44 | 4665.30 | – | – |
 Simeprevir 150 mg | – | – | – | – | – | – | – | – | 3610.29 | 6494.49 |
Total | 20,119.28 | 36,192.27 | 36,110.79 | 64,959.15 | 44,497.97 | 80,046.72 | 9359.12 | 16,835.98 | 10,375.97 | 18,665.17 |
TOTAL COST | 24,020.16 | 43,176.28 | 39,578.23 | 71,196.03 | 47,946.92 | 86,250.33 | 10,985.90 | 19,761.72 | 12,002.75 | 21,590.91 |