The red distribution width and the platelet distribution width as prognostic predictors in gastric cancer

BMC Gastroenterology

Table 3 Univariate and multivariate survival analysis results of 227 patients with GC

Clinicopathological feature	Univariate^a(OS)		Multivariate^b(OS)		Univariate^a(DFS)		Multivariate^b(DFS)
Clinicopathological feature	HR (95% CI)	P value	HR(95% CI)	P value	HR (95% CI)	P value	HR(95% CI)	P value
RDW(<13/≥13)	1.801 (0.985–3.291)	0.056			1.807 (1.015–3.217)	0.044
PDW(<11.5/≥11.5)	0.701 (0.385–1.275)	0.244			0.754 (0.425–1.337)	0.333
Gender(Male/Female)	0.764 (0.355–1.648)	0.493			0.908 (0.452–1.827)	0.787
Age(<60/≥60)	1.541 (0.844–2.814)	0.160			1.535 (0.863–2.730)	0.044
Tumor diameter(≤4/>4)	2.890 (1.553–5.375)	0.001			2.633 (1.465–4.731)	0.001
Differentiation (Well/Moderate/ Poor)	1.968 (1.027–3.772)	0.041			1.650 (0.926–2.941)	0.089
Depth of tumor (T1 + T2/T3 + T4)	2.169 (1.613–2.916)	< 0.001	1.722(1.170–2.535)	0.006	2.097 (1.569–2.802)	< 0.001	1.655(1.130–2.422)	0.010
Lymph node metastasis (N0/N1 + N2 + N3)	5.548 (2.335–13.181)	< 0.001			4.548 (2.118–9.763)	< 0.001
Distance metastasis (M0/M1)	2.403 (1.112–5.193)	0.026			2.137 (0.996–4.584)	0.051
pStage(I + II/III + IV)	7.841 (3.075–19.994)	< 0.001	4.311(1.591–11.682)	0.004	6.179 (2.755–13.858)	< 0.001	3.517(1.470–8.413)	0.005
CEA(≤5/>5)	1.240 (0.552–2.788)	0.602			1.116 (0.500–2.492)	0.789
CA125(≤35/>35)	2.606 (0.353–19.240)	0.348			2.606 (0.353–19.240)	0.348
CA199(≤39/>39)	2.405 (1.173–4.930)	0.017			2.478 (1.249–4.917)	0.009

Abbreviations: OS overall survival, DFS disease-free survival, HR hazard ratio, CI confidence interval, RDW red blood cell distribution width, CEA carcinoembryonic antigen, CA125 carbohydrate antigen 125, CA199 carbohydrate antigen 199
^aPerformed using the Kaplan–Meier analysis model and the log-rank test; values of P < 0.05 in the univariate analysis were entered into a multivariate analysis
^bperformed using Cox proportional hazards models with the forward likelihood method

ISSN: 1471-230X