Skip to main content

Table 3 COX-1 and COX-2 expression based on real time polymerase chain reaction in colonic biopsies from CRN-pts and ctrls

From: Combined activity of COX-1 and COX-2 is increased in non-neoplastic colonic mucosa from colorectal neoplasia patients

 

COX-1 expression, SEM

COX-2 expression, SEM

p-value

CRN-pts (N/n = 11/11)

0.024 ± 0.003

0.007 ± 0.002

0.012 *

Ctrls (N/n = 7/7)

0.020 ± 0.003

0.005 ± 0.002

<  0.001 *

p-value

0.24

0.43

 
  1. Horizontal p-values to the right compare COX-1 expression with COX-2 expression for CRN-pts and ctrls. Vertical p-values at the bottom compare CRN-pts with ctrls for COX-1 and COX-2 expression. Total or combined expression of COX enzyme is defined as expression of COX-1 + COX-2. The combined COX expression was 0.015 ± 0.003 for CRN-pts and 0.012 ± 0.003 for ctrls; p = 0.35. CRN-pts represent values for biopsies from colorectal neoplasia patients and ctrls values are for biopsies from patients without colorectal neoplasia. N = number of patients, n = number of biopsies, in parenthesis (N/n). * p-value < 0.05
Back to article page

BMC Gastroenterology

ISSN: 1471-230X

Contact us