NAFLD without DIOS (n = 22) | NAFLD with DIOS (n = 16) | ||
---|---|---|---|
With serum ferritin < 350 μg/L (n = 15) | With serum ferritin > 350 μg/L (n = 7) | ||
Serum hepcidin (μg/L) | 24 ± 19 | 37 ± 13 | 53 ± 28* |
Serum ferritin (μg/L) | 156 ± 78* | 621 ± 170 | 816 ± 285 |
Transferrin saturation (%) | 28 ± 8 | 25 ± 10 | 39 ± 9# |
Liver iron score | 0.03 ± 0.13 | 0.14 ± 0.24 | 2.13 ± 0.92* |
CRP (mg/L) | 2.7 ± 2.2 | 3.7 ± 4.2 | 1.8 ± 0.91 |
Plasma-triglycerides (mmol/L) | 2.89 ± 1.09 | 1.83 ± 1.09 | 1.95 ± 0.90 |
Plasma cholesterol (mmol/L) | 5.18 ± 0.96 | 5.25 ± 0.84 | 5.25 ± 0.71 |
TNF-α (ng/L) | 6.27 ± 5.13 | 137 ± 316 | 8.37 ± 5.82 |
IL-6 (ng/L) | 2.47 ± 1.71 | 32.3 ± 62.7 | 2.36 ± 1.02 |
NAS | 4.5 ± 1.8 | 3.6 ± 1.7 | 4.4 ± 1.8 |
Steatosis (grade) | 2.07 ± 0.80 | 2.00 ± 1.00 | 2.72 ± 0.65 |
Ballooning | 1.07 ± 0.59 | 0.80 ± 0.84 | 0.63 ± 0.67 |
Lobular inflammation | 1.20 ± 0.86 | 1.00 ± 0.71 | 1.00 ± 1.00 |
Portal inflammation | 0.27 ± 0.46 | 0.60 ± 0.55 | 0.18 ± 0.40 |
Fibrosis | 1.33 ± 0.90 | 2.00 ± 1.00 | 2.72 ± 0.65 |