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Table 1 Subject characteristics, basal and postprandial FGF19 serum concentrations

From: Response of fibroblast growth factor 19 and bile acid synthesis after a body weight-adjusted oral fat tolerance test in overweight and obese NAFLD patients: a non-randomized controlled pilot trial

Variables

Control

Overweight

Obesity

p-value

N (men/women)

16 (7/9)

14 (8/6)

12 (6/6)

n.s.a

Age (years)

29.5 (24.0–53.0)

49.0 (38.8–57.3)

48.0 (37.0–57.3)

0.551b

BMI (kg/m2)

24.2 (21.8–26.6)

28.3 (26.3–29.2)

35.3 (32.7–39.0)

<  0.001b

FGF19 (pg/ml)

 t = 0 h

178.5 (101.0–257.0)c

127.5 (70.0–161.3)

116.0 (51.0–134.3)c

0.01c

 t = 2 h

244.5 (161.5–377.5)c

163.0 (78.5–168.3)c

181.0 (85.3–393.0)

0.004c

 t = 4 h

332.5 (202.0–590.8)

207.0 (112.5–365.0)

220.0 (138.8–385.3)

0.445b

 t = 6 h

211.0 (165.3–296.3)

154.0 (124.0–254.0)

184.5 (110.5–274.3)

0.445b

  1. All data are given as median (interquartile range)
  2. aChi-square-test
  3. bKruskal-Wallis-test
  4. cMann-Whitney-U-test