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Table 2 Basal and postprandial BA and C4 serum concentrations

From: Response of fibroblast growth factor 19 and bile acid synthesis after a body weight-adjusted oral fat tolerance test in overweight and obese NAFLD patients: a non-randomized controlled pilot trial

Variables

Control

Overweight

Obesity

p-value

N (men/women)

16 (7/9)

14 (8/6)

12 (6/6)

n.s.a

Bile acids (μM)

 t = 0 h

1.1 (0.8–1.7)

1.5 (0.8–2.2)

1.4 (0.9–1.7)

0.343

 t = 2 h

1.4 (1.1–4.7)

2.1 (1.2–3.8)

2.4 (1.6–4.1)

0.311

 t = 4 h

1.1 (0.7–2.0)

2.0 (1.3–2.5)

2.0 (1.0–2.3)

0.155

 t = 6 h

0.7 (0.5–1.6)

1.3 (0.8–2.0)

1.2 (0.8–1.7)

0.087

C4 (nM)

 t = 0 h

41.4 (7.0–69.2)

58.5 (12.8–91.6)

35.1 (1.2–72.3)

0.422

 t = 2 h

28.1 (7.1–49.6)

43.1 (10.0–114.0)

35.7 (1.2–118.3)

0.765

 t = 4 h

13.0 (6.8–44.7)

40.8 (21.1–99.3)

32.7 (3.3–108.0)

0.343

 t = 6 h

11.8 (4.1–34.4)

40.7 (18.1–80.1)

28.6 (3.5–82.4)

0.445

  1. All data are given as median (interquartile range), p-values: Kruskal-Wallis-test,aChi-square-test