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Table 7 Multivariate analysis of factors associated with En bloc resection, complete resection, and procedure-related perforation

From: Endoscopic submucosal dissection under general anesthesia for superficial esophageal squamous cell carcinoma is associated with better clinical outcomes

Variables

En bloc resection

Complete resection

Perforation

OR (95% CI)

p-value

OR (95% CI)

p-value

OR (95% CI)

p-value

Age

1.009 (0.921–1.105)

0.844

0.9991 (0.944–1.041)

0.713

1.029 (0.948–1.116)

0.494

Tumor location

 

0.950

 

0.376

 

0.647

 Upper thoracic

1

 

1

 

1

 

 Middle thoracic

N/A

0.998

0.822 (0.171–3.959)

0.807

0.483 (0.034–6.948)

0.592

 Lower thoracic

N/A

0.998

1.203 (0.276–5.240)

0.805

0.259 (0.020–3.309)

0.298

 Esophagogastric Jx

N/A

1.000

0.140 (0.007–2.640)

0.189

N/A

0.999

Tumor morphology

 

0.734

 

0.955

 

0.933

 IIa

1

 

1

 

1

 

 IIb

4.775 (0.318–71.736)

0.258

0.830 (0.253–2.728)

0.759

N/A

0.998

 IIc

N/A

0.998

1.063 (0.225–5.030)

0.939

N/A

0.998

 Mixed

N/A

1.000

0.511 (0.024–10.810)

0.666

N/A

1.000

Gross tumor size (cm)

0.294 (0.063–1.374)

0.120

1.320 (0.630–2.768)

0.462

0.907 (0.236–3.488)

0.888

Resected specimen size (cm)

1.147 (0319–4.126)

0.834

0.475 (0.228–0.989)

0.047

1.926 (0.580–6.397)

0.285

Depth of tumor invasion

 

0.744

 

0.228

 

0.924

 Mucosal cancer

1

 

1

 

1

 

 SM invasion

1.467 (0.147–14.623)

 

0.567 (0.226–1.427)

 

0.916 (0.150–5.596)

 

Experience of endoscopist

 

0.098

 

0.146

 

0.052

 First 10 esophageal ESDs

1

 

1

 

1

 

 Further esophageal ESDs

0.226 (0.039–1.315)

 

0.513 (0.208–1.262)

 

0.289 (0.082–1.011)

 

Method of sedation

 

0.996

 

0.011

 

0.030

 Conscious sedation

1

 

1

 

1

 

 General anesthesia

N/A

 

3.401 (1.317–8.785)

 

0.067 (0.006–0.775)

 
  1. OR odds ratio, CI confidence interval, ESD endoscopic submucosal dissection