Table 4 Association of SPARCL1 expression with clinicopathological factors of gastric GIST (n = 98)
From: Secreted protein acidic and rich in cysteine-like 1 suppresses metastasis in gastric stromal tumors
Variables | SPARCL1 expression | P value | |
|---|---|---|---|
SPARCL1-low | SPARCL1-high | ||
Gender | 0.182 | ||
Male | 10 (37.04) | 37 (52.11) | |
Female | 17 (62.96) | 34 (47.89) | |
Age (years) | 55.67 ± 14.11 | 57.89 ± 10.46 | 0.398 |
Surgical margins | 0.062 | ||
R0 | 24 (88.89) | 70 (98.59) | |
Not R0 | 3 (11.11) | 1 (1.41) | |
Multivisceral resection (n, %) | 7 (25.93) | 2 (2.82) | 0.002 |
Tumor rupture (n, %) | 1 (3.70) | 0 (0.00) | 0.276 |
Hepatic metastasis at initial diagnosis (n, %) | 5 (18.52) | 0 (0.00) | 0.001 |
Peritoneal metastasis at initial diagnosis (n, %) | 7 (25.93) | 0 (0.00) | < 0.001 |
Tumor size (cm) | 11.94 ± 9.04 | 5.63 ± 3.24 | < 0.001 |
Mitotic count (n, %) | < 0.001 | ||
≤5/50 HPF | 3 (11.11) | 35 (49.30) | |
6~ 10/50 HPF | 9 (33.33) | 20 (28.17) | |
> 10/50 HPF | 15 (55.56) | 16 (22.54) | |
NIH risk classification (n, %) | 0.127 | ||
Very low | 0 (0.00) | 4 (5.63) | |
Low | 1 (3.70) | 20 (28.17) | |
Intermediate | 4 (14.81) | 22 (30.99) | |
High | 22 (81.48) | 25 (35.21) | |