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Table 1 Univariate analysis of potential risk factors for the development of acute cholecystitis after ERCP

From: Risk factors for post-ERCP cholecystitis: a single-center retrospective study

Variable

Acute Cholecystitis

Statistic

P

No (n = 2636)

Yes (n = 36)

Age (y), Mean ± SD

62.4 ± 16.28

62.2 ± 12.90

t = 0.097

0.923

Female

1145 (43.4%)

21 (58.3%)

x2 = 2.627

0.105

Past history

    

 Hypertension

976 (37.0%)

13 (36.1%)

x2 = 0.013

0.910

 Hyperlipemia

70 (2.7%)

1 (2.9%)

x2 = 0.005

0.942

 Diabetes mellitus

473 (18.0%)

7 (20.0%)

x2 = 0.098

0.755

 Acute pancreatitis

459 (17.4%)

16 (44.4%)

x2 = 17.754

< 0.001

 Acute cholangitis

532 (20.2%)

6 (16.7%)

x2 = 0.273

0.601

 Chronic cholecystitis

1427 (54.1%)

33 (91.7%)

x2 = 20.185

< 0.001

Antibiotics before ERCP

948 (36.0%)

11 (30.6%)

x2 = 0.451

0.601

Gallbladder opacification

1016 (38.5%)

24 (66.7%)

x2 = 11.816

0.001

Diameter of CBD(cm)

1.2 ± 0.48

1.1 ± 0.42

t = 1.237

0.216

Temperature before ERCP (°C)

36.6 ± 0.58

36.8 ± 0.84

t = −1.891

0.059

Bile duct stents

  

x2 = 15.805

0.001

 No stent

1174 (66.2%)

19 (52.8%)

  

 Metallic stent

414 (15.7%)

14 (38.9%)

  

 Plastic stent

436 (16.5%)

2 (5.6%)

  

 Metallic+plastic stent

42 (1.6%)

1 (2.8%)

  

Laboratory index before ERCP (Median,P25,P75)

 ALT

83.0 (37.3, 193.3)

58.7 (37.5, 191.0)

Z = −0.027

0.979

 AST

54.9 (27.9, 119.0)

53.5 (28.7, 83.8)

Z = −0.143

0.886

 AKP

198.1 (114.9, 359.8)

196.3 (94.2, 321.2)

Z = −0.414

0.679

 GGT

292.5 (125.7, 550.2)

246.9 (91.9, 543.8)

Z = −0.181

0.856

 TB

34.9 (15.5, 126.8)

23.7 (13.7, 83.3)

Z = −0.845

0.391

 DB

21.2 (6.7, 98.8)

12.8 (7.1, 73.4)

Z = −0.641

0.522

 WBC

6.1 (4.8, 8.2)

7.9 (5.9, 11.0)

Z = −3.610

< 0.001

 Hemoglobin

125.0 (111.0, 136.0)

131.0 (121.0, 138.0)

Z = −1.413

0.158

 Platelet count

192.0 (148.0, 245.0)

192.0 (146.0, 276.0)

Z = −0.210

0.833

  1. CBD common bile duct, ALT alanine aminotransferase, AST aspartate anminotransferase, AKP alkaline phosphatase, GGT gamma-glutamyltranspeptidase, TB total bilirubin, DB direct bilirubin, WBC white blood cell