Fig. 6From: Apatinib affect VEGF-mediated cell proliferation, migration, invasion via blocking VEGFR2/RAF/MEK/ERK and PI3K/AKT pathways in cholangiocarcinoma cella Protein expression of p-VEGFR2, VEGFR2, RAF, p-MEK, MEK, p-ERK1/2, ERK1/2, p-AKT and AKT in transfected QBC939 cells post 100 ng/ml rhVEGF or 100 ng/ml rhVEGF + 100 ng/ml apatinib treatment. GAPDH was detected as reference. b Densitometric analysis of the autoradiographic plaques of these proteins is shown on the Fig. 6a . *P < 0.05Back to article page