|  | Total n = 235 | NM n = 173 | WM n = 62 | Univariate analysis | Multivariate analysisa | ||
---|---|---|---|---|---|---|---|---|
p | OR (95% CI) | p | OR (95% CI) | |||||
Age | > 62 | 115 | 95 | 20 | 0.003 | 1 | < 0.001 | 1 |
 | ≤62 | 120 | 78 | 42 |  | 2.55 (1.39, 4.71) |  | 3.97 (1.87, 8.42) |
Sex | Female | 84 | 68 | 16 | 0.057 | 1 | 0.011 | 1 |
 | Male | 151 | 105 | 46 |  | 1.86 (0.98, 3.55) |  | 2.79 (1.26, 6.19) |
Pain | No | 85 | 67 | 18 | 0.174 | 1 | Â | Â |
 | Yes | 150 | 106 | 44 |  | 1.50 (0.82, 2.90) |  |  |
Jaundice | No | 162 | 112 | 50 | 0.022 | 1 | Â | Â |
 | Yes | 73 | 61 | 12 |  | 0.44 (0.22, 0.89) |  |  |
Weight loss | No | 135 | 103 | 32 | 0.280 | 1 | Â | Â |
 | Yes | 100 | 70 | 30 |  | 1.37 (0.77, 2.47) |  |  |
Smoking | No | 187 | 139 | 48 | 0.624 | 1 | Â | Â |
 | Yes | 48 | 34 | 14 |  | 1.19 (0.59, 2.41) |  |  |
Drinking | No | 197 | 141 | 56 | 0.112 | 1 | Â | Â |
 | Yes | 38 | 32 | 6 |  | 0.47 (0.19, 1.19) |  |  |
Hypertension | No | 71 | 51 | 20 | 0.683 | 1 | Â | Â |
 | Yes | 164 | 122 | 42 |  | 1.14 (0.61, 2.13) |  |  |
Diabetes | No | 199 | 148 | 51 | 0.538 | 1 | Â | Â |
 | Yes | 36 | 25 | 11 |  | 1.28 (0.59, 2.78) |  |  |
Interval between imaging and surgery | ≤7 | 170 | 123 | 47 |  | 1 |  |  |
7–14 | 48 | 39 | 9 | 0.213 | 0.60 (0.27, 1.34) |  |  | |
≥14 | 17 | 11 | 6 | 0.461 | 1.49 (0.52, 4.31) |  |  | |
Tumor size | < 4.0 | 96 | 92 | 4 | < 0.001 | 1 | < 0.001 | 1 |
 | ≥4.0 | 139 | 81 | 58 |  | 16.47 (5.73, 47.36) |  | 16.02 (5.31, 48.30) |
Tumor location | Head | 174 | 134 | 40 | 0.048 | 1 | Â | Â |
 | Body/tail | 61 | 39 | 22 |  | 1.88 (1.01, 3.55) |  |  |
ALT | ≥125 | 71 | 64 | 7 | < 0.001 | 1 | < 0.001 | 1 |
 | < 125 | 164 | 109 | 55 |  | 4.61 (1.98, 10.74) |  | 6.19 (2.26, 16.92) |
AST | ≥ 85 | 75 | 64 | 11 | 0.006 | 1 |  |  |
 | < 85 | 160 | 109 | 51 |  | 2.72 (1.32, 5.60) |  |  |
TBil | ≥75 | 78 | 65 | 13 | 0.019 | 1 |  |  |
 | < 75 | 157 | 108 | 49 |  | 2.27 (1.14, 4.50) |  |  |
DBil | ≥50 | 75 | 61 | 14 | 0.069 | 1 |  |  |
 | < 50 | 160 | 112 | 48 |  | 1.87 (0.95, 3.66) |  |  |
ALB | ≥40 | 124 | 89 | 35 | 0.498 | 1 |  |  |
 | < 40 | 111 | 84 | 27 |  | 0.82 (0.46, 1.47) |  |  |
AFP | < 3.0 | 153 | 111 | 42 | 0.612 | 1 |  |  |
 | ≥3.0 | 82 | 62 | 20 |  | 0.85 (0.46, 1.57) |  |  |
CA19–9 | < 385 | 144 | 115 | 29 | 0.007 | 1 | 0.015 | 1 |
 | ≥385 | 91 | 58 | 33 |  | 2.26 (1.25, 4.07) |  | 2.49 (1.19, 5.21) |
CEA | < 9 | 183 | 145 | 38 | < 0.001 | 1 |  |  |
 | ≥9 | 52 | 28 | 24 |  | 3.53 (1.87, 6.67) |  |  |