Table 1 Demographics and Baseline Disease characteristics of children with Crohn’s Disease, n = 33
Demographics | n (%) or Mean ± SD or Median (range) | ||
|---|---|---|---|
Gender | |||
Males | 22 (67%) | ||
Females | 11 (33%) | ||
Race | |||
Chinese | 14 (43%) | ||
Malay | 6 (18%) | ||
Indian | 10 (30%) | ||
Others | 3 (9%) | ||
Median Age at presentation, years | 13y (range 3–17) | ||
BMI z-score | −1.38 ± 1.57 | ||
Disease location | |||
L1 terminal ileum | 2 (6%) | ||
L2 colon | 8 (24%) | ||
L3 ileo-colonic | 23 (70%) | ||
L4, upper GI | 13 (39%) | ||
Disease behavior | |||
B1 Non-stricturing | 28 (85%) | ||
B2 Stricturing | 3 (9%) | ||
B3 Penetrating | 0 (0%) | ||
B2B3 Stricturing and Penetrating | 2 (6%) | ||
Perianal involvement | 4 (12%) | ||
Clinical parameters | Pre-EEN | Post-EEN | p-value |
PCDAI baseline | 32.7 ± 9.2 | 4.2 ± 5.1 | < 0.0001 |
BMI z-score | −1.38 ± 1.57 | − 0.82 ± 1.27 | 0.004 |
Weight (kg) | 36.9 ± 14.36 kg | 38.18 kg ± 12.62 | < 0.001 |
Weight z-sore | −1.31 ± 1.75 | − 0.84 ± 1.32 | 0.0001 |
Height (cm) | 147.1 ± 18.8 cm | 149.2 cm ± 18.72 | 0.009 |
Height z-score | − 0.58 ± 1.45 | 0.39 ± 1.49 | 0.009 |
Hemoglobin g/dL | 11.4 ± 1.5 | 12.2 ± 1.5 | 0.008 |
Albumin g/L | 30.7 ± 7.5 | 38.7 ± 3.9 | < 0.0001 |
Platelets ×109 | 464 ± 161 | 370 ± 111 | < 0.0001 |
ESR mm/h | 51.6 ± 30.1 | 13.3 ± 7.1 | < 0.0001 |
CRP mg/L | 44.6 ± 51.0 | 5.2 ± 7.6 | 0.001 |