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Table 3 The predictive discrimination ability of the nomogram compared to the MELD, CTP, and SOFA score systems in the primary and validation cohorts

From: Development and external validation of a prognostic nomogram for acute decompensation of chronic hepatitis B cirrhosis

 

C-index

95% CI for C-index

Goodness of Fit

Comparison of models

Lower

Upper

LR

R2

Dxy

SD

Z

P value

Primary cohort (n = 509)

 MELDs

0.820

0.764

0.878

72.07

0.185

−0.343

0.083

−4.12

< 0.001

 CTPs

0.793

0.744

0.842

70.79

0.175

−0.687

0.051

−13.5

< 0.001

 SOFAs

0.868

0.829

0.907

119.46

0.282

−0.398

0.075

−5.33

< 0.001

 CLIF-C ADs

0.716

0.636

0.796

45.36

0.121

−0.476

0.078

−6.10

< 0.001

 Nomogram

0.897

0.850

0.943

165.63

0.374

 

Validation cohort (n = 620)

 MELDs

0.826

0.794

0.857

238.69

0.336

0.451

0.045

10.13

< 0.001

 CTPs

0.741

0.707

0.776

130.11

0.196

−0.557

0.035

−15.94

< 0.001

 SOFAs

0.837

0.807

0.866

255.24

0.349

−0.215

0.049

−4.39

< 0.001

 CLIF-C ADs

0.569

0.525

0.615

8.47

0.015

−0.501

0.041

−12.22

< 0.001

 Nomogram

0.839

0.811

0.867

268.38

0.363