Skip to main content

Table 3 HLA-DQ data in relation to clinical and analytical features stratified by family history in CD

From: Influence of HLA on clinical and analytical features of pediatric celiac disease

 

Sex

n = 463

Clinical Presentation

n = 463

Histological Damage

n = 458

Anti-TG2/EMA

n = 275

Anti-TG2 Levels

n = 172

M

F

Classical

Non-Classical

M3b + M3c

Milder lesion

Positive

Negative

≥100

< 100

Family History

HLA-DQ2.5 double dose

10

66.7%

5

33.3%

4

28.6%

10

71.4%

13

92.9%

1

7.1%

12

100%

0

6

75%

2

25%

Other HLA-DQ

3

42.9%

4

57.1%

3

37.5%

5

62.5%

8

100%

0

5

100%

0

3

60%

2

40%

Non-Family History

HLA-DQ2.5

double dose

68

39.1%

106

60.9%

162

92.6%

13

7.4%

164

94.8%

9

5.2%

110

99.1%

1

0.9%

43

70.5%

18

29.5%

Other HLA-DQ

94

35.2%

173

64.8%

229

86.1%

37

13.9%

232

88.2%

31

11.8%

153

93.3%

11

6.7%

67

68.4%

31

31.6%