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Table 3 Univariate association with outcome

From: Typical symptoms and not positive reflux-cough correlation predict cure of gastroesophageal reflux disease related chronic cough after laparoscopic fundoplication: a retrospective study

Variable

Outcome

P value

Cured

Not cured

Age

  ≥ 60

25 (61%)

16 (39%)

 

  < 60

22 (57.9%)

16 (42.1%)

0.78

Sex

 Male

25 (58.1%)

18 (41.9%)

 

 Femal

22 (61.1%)

14 (38.9%)

0.789

Hypertension

 Yes

11 (55%)

9 (45%)

 

 No

36 (61%)

23 (39%)

0.636

Diabetes

 Yes

3 (100%)

0 (0%)

 

 No

44 (57.9%)

32 (42.1%)

0.391

Coronary heart disease

 Yes

1 (33.3%)

2 (66.7%)

 

 No

46 (60.5%)

30 (39.5%)

0.733

Heartburn

 Yes

38 (64.4%)

21 (35.6%)

 

 No

9 (45.0%)

11 (55.0%)

0.127

Regurgitation

 Yes

40 (64.5%)

22 (35.5%)

 

 No

7 (41.2%)

10 (58.8%)

0.082

Typical symptoms

 Yes

44 (64.7%)

24 (35.3%)

 

 No

3 (27.3%)

8 (72.7%)

0.044

Asthma

 Yes

17 (73.9%)

6 (26.1%)

 

 No

30 (53.6%)

26 (46.4%)

0.094

Hiatal hernia

 Yes

35 (60.3%)

23 (39.7%)

 

 No

12 (57.1%)

9 (42.9%)

0.798

Esophagitis

 Yes

21 (56.8%)

16 (43.2%)

 

 No

26 (61.9%)

16 (38.1%)

0.642

Barrett’s esophagus

 Yes

7 (77.8%)

2 (22.2%)

 

 No

40 (57.1%)

30 (42.9%)

0.409

Reflux of bile

 Yes

6 (40%)

9 (60%)

 

 No

41 (64.1%)

23 (35.9%)

0.088

DeMeester scores

  ≥ 14.7

22 (55%)

18 (45%)

 

  < 14.7

25 (64.1%)

14 (35.9%)

0.41

Acid exposure time

  ≥ 4.2%

22 (56.4%)

17 (43.6%)

 

  < 4.2%

25 (62.5%)

15 (37.5%)

0.581

Bolus exposure time

  ≥ 1.4%

29 (53.7%)

25 (46.3%)

 

  < 1.4%

18 (72%)

7 (28%)

0.123

Number of Reflux episodes (impedance)

  ≥ 73

18 (47.4%)

20 (52.6%)

 

  < 73

29 (70.7%)

12 (29.3%)

0.035

SI of chronic cough

  > 50%

17 (58.6%)

12 (41.4%)

 

  ≤ 50%

30 (60%)

20 (40%)

0.904

SAP of chronic cough

  > 95%

22 (56.4%)

17 (43.6%)

 

  ≤ 95%

25 (62.5%)

15 (37.5%)

0.581

Reflux-cough correlation

 Positive

26 (56.5%)

20 (43.5%)

 

 Negative

21 (63.6%)

12 (36.4%)

0.525

Ineffective esophageal motility

 Yes

9 (40.9%)

13 (59.1%)

 

 No

36 (69.2%)

16 (30.8%)

0.023