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Fig. 2 | BMC Gastroenterology

Fig. 2

From: SNHG 6 promotes the progression of Colon and Rectal adenocarcinoma via miR-101-3p and Wnt/β-catenin signaling pathway

Fig. 2

miR-101-3p was an inhibitory target of lncRNA SNHG6. a Sequence alignment of miR-101-3p with the putative binding sites with in the wild-type regions of SNHG6. Dual-luciferase reporter assay showed that miR-101-3p mimics reduced the intensity of fluorescence in HEK293T cells transfected with SNHG6-Wild type, while had no effect on the SNHG6-mutant vector. b Relative expression of SNHG6 after CRC cells transfected with si-SNHG6 or si-NC. c qRT-PCR analysis of miR-101-3p expression in HCT116 and SW620 cells transfected with si-SNHG6 or si-NC. d qRT-PCR analysis of SNHG6 expression in HCT116 and SW620 cells transfected with miR-101-3p or miR-NC. *P < 0.05; **P < 0.01; ***P < 0.001

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