Fig. 2From: Histological, immunohistochemical and mRNA gene expression responses in coeliac disease patients challenged with gluten using PAXgene fixed paraffin-embedded duodenal biopsiesMucosal morphology in gluten challenge. The measurement of villous height, crypt depth and villous height: crypt depth ratio in non-coeliac disease control patients, in coeliac disease patients on a gluten-free diet (GFD) before gluten challenge and then in coeliac disease patients after the gluten challenge. There was no significant change in non-coeliac disease control patients or coeliac disease on a gluten-free diet in any parameter, but as expected, significant changes were seen between the samples taken before and after the gluten challenge in coeliac disease patientsBack to article page