Irritable bowel syndrome-like symptoms and health related quality of life two years after Roux-en-Y gastric bypass - a prospective cohort study

Table 4 Changes in Physical Component Scores (PCS) and Mental Component Scores (MCS) from preoperatively to two year after Roux-en-Y Gastric bypass (RYGB)

Group (number of participants)	n	Δ PCS	95% CI	p-value	Δ MCS	95% CI	p-value
All participants	153	7.1	5.4 to 8.8	<0.001	−1,25	−2.9 to 0.44	0.15
Subgroups based on IBS at preoperative visit:
With IBS	10	0.54	−8.6 to 9.7	0.90	−2.6	−8.5 to 3.2	0.33
Without IBS	143	7.6	5.8 to 9.3	<0.001	−1.2	−2.9 to 0.62	0.20
Subgroups based on IBS-like symptoms 2 years after RYGB:
Never IBS or IBS-like symptoms	113	7.68	5.8 to 9.6	<0.001	0.29	−1.5 to 2.1	0.75
New onset IBS-like symptoms	30	7.15	2.8 to 11.5	0.002	−6.59	−11.3 to − 1.9	0.007
IBS at preoperative and IBS-like symptoms 2 year follow-up visit	6	−3.3	−14.1 to 7.5	0.47	−4.9	−14.8 to 5.0	0.26

All participants, and subgroups based on status of irritable bowel syndrome (IBS) are presented. Significant p-values are marked in bold
The SF-36 questionnaires were scored using the QualityMetric Health Outcomes™ Scoring Software 4.5 giving the presented Physical Component Scores (PCS) and Mental Component Scores (MCS)
The presented delta values: SF-36 value at the 2 year follow-up visit - SF-36 value at the preoperative visit. Positive delta values indicate improved score after RYGB and negative values indicate worsened score after RYGB. The results are given as mean values with 95% confidence intervals (CI). Data were analyzed with paired t-tests
New onset IBS-like symptoms: no IBS before RYGB, but IBS-like symptoms 2 years after RYGB. Never IBS or IBS-like symptoms: No IBS before or IBS-like symptoms 2 years after RYGB
Missing data: All participants; n = 80. Subgroups based on IBS at preoperative visit: with IBS; n = 17, without IBS; n = 63. Subgroups based on IBS-like symptoms 2 years after RYGB: never IBS or IBS-like symptoms; n = 48, new onset IBS-like symptoms; n = 15, IBS at preoperative and IBS-like symptoms 2 year follow-up visit; n = 10

ISSN: 1471-230X