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Fig. 3 | BMC Gastroenterology

Fig. 3

From: Three cases of histologically proven hepatic epithelioid hemangioendothelioma evaluated using a second-generation microbubble contrast medium in ultrasonography: case reports

Fig. 3

a In the conventional abdominal US in case 3, there were multiple low echoic liver nodules, predominantly seen in the right lobe (arrow). b In the DWI at a b score of 1000 (sec/mm2), the peripheral site of the nodules showed a much higher intensity than its central lesion. c ADC mapping is shown. d The early vascular phase of CEUS in case3 showed that the tumors were gradually enhanced from the peripheral sites. e In the PVLP and post vascular phase, they were defective. f Photomicrograph of a histological section of a hepatic specimen obtained via percutaneous liver needle biopsy in case 3 (200× with hematoxylin and eosin stain) is shown. g A high number of epithelioid tumor cells with spindle-shaped nuclei, form intracellular vascular lumina (arrow) (800× with hematoxylin and eosin stain). In immunostaining (200×), the sample was positive for cluster of differentiation (CD) 31 (h) and CD34 (i)

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