Fig. 1From: Clinical impact of the perioperative management of oral anticoagulants in bleeding after colonic endoscopic mucosal resectionManagement of anticoagulants. The administration of warfarin is generally continued within the therapeutic range of the prothrombin time-international normalized ratio (PT-INR). For patients taking warfarin with low-thromboembolic risk, 3 days withdrawal of warfarin is performed. In heparin bridging therapy, the administration of warfarin is discontinued for 3 days, and heparin is intravenously administered for 2 days. The administration of heparin is stopped 4–6 h before the procedure and is immediately restarted with warfarin after surgery. A direct oral anticoagulant (DOAC) is orally administered on the day before the procedure, and administration is restarted on the morning of postoperative day (POD) 1Back to article page