Skip to main content

Table 2 Changes in tacrolimus blood concentration (Tc) and RCA, RPA, AST after liver transplantation

From: RETRACTED ARTICLE: Approaching treatment for immunological rejection of living-donor liver transplantation in rats

 

0.5d

1d

2d

3 d

4d

5d

6d

RCA

0.269 ± 0.030

0.310 ± 0.021

0.452 ± 0.015

0.590 ± 0.041

0.621 ± 0.053

0.756 ± 0.049

0.789 ± 0.056

RPA

0.76 ± 0.089

0.88 ± 0.098

1.39 ± 0.01

4.8 ± 0.14*

5.2 ± 0.25

6.5 ± 0.36

6.9 ± 0.49

AST

895.1 ± 168.8

1186.6 ± 378.2

1120.5 ± 298.5

599.1 ± 277.7*

419.9 ± 201.2

227.6 ± 140.9

189.1 ± 110.3

T C/D

10.03 ± 1.15

11.46 ± 1.59

13.58 ± 2.01

12.21 ± 2.68

10.89 ± 2.35

8.01 ± 1.98

6.16 ± 1.24

  1. *P < 0.01 versus 2 days, RCA (Ratio of CYP3A4 to actin), RPA(Ratio of proliferation to apoptosis), AST(asparatate aminotransferase), TC/D (tacrolimus blood concentration/dose ratio)