Table 3 The microscopic features of the small bowel mucosa among the three groups
From: Microscopic features of small bowel mucosa of patients with Crohn’s disease
CD cases(ratio) | suspected CD cases(ratio) | non-CD cases(ratio) | P | ||
|---|---|---|---|---|---|
Cases | 137 | 20 | 96 | ||
Histopathological parameters | |||||
No. | Microscopic features | ||||
1 | Inflammation depth | 0.001 | |||
SM† | 10(7.30%) | 0(0.00%) | 3(3.13%) | ||
M† | 127(92.70%) | 20(100.00%) | 93(96.87%) | ||
2 | Uneven inflammation | 114(83.21%) | 10(50.00%) | 38(39.58%) | 0.000 |
3 | Cryptisis/Crypt abscesses | 42(30.66%) | 4(20.00%) | 15(15.63%) | 0.029 |
4 | Intraepithelium neutrophil | 41(29.93%) | 4(20.00%) | 10(10.42%) | 0.002 |
5 | Intramucosa neutrophil | 51(37.23%) | 6(30.00%) | 17(17.71%) | 0.006 |
6 | Capillaries increase | 14(10.22%) | 2(10.00%) | 7(7.29%) | 0.797 |
7 | Basal plasmacytosis | 25(18.25%) | 1(5.00%) | 8(8.33%) | 0.041 |
8 | Erosion | 39(28.47%) | 3(15.00%) | 14(14.58%) | 0.029 |
9 | Pyloric gland metaplasia | 30(21.90%) | 7(35.00%) | 7(7.29%) | 0.001 |
10 | Abberant crypt stucture | 120(87.59%) | 16(80.00%) | 52(54.17%) | 0.000 |
11 | Villus changes | 114(83.21%) | 14(70.00%) | 50(52.08%) | 0.000 |
12 | Goblet cells increase | 83(60.58%) | 9(45.00%) | 17(17.71%) | 0.000 |
13 | Intraepithelium mucus decrease | 34(24.82%) | 7(35.00%) | 11(11.46%) | 0.011 |
14 | Lymphangiectasis | 47(34.30%) | 4(20.00%) | 10(10.42%) | 0.000 |
15 | Thickened muscularis mucosa | 54(39.42%) | 2(10.00%) | 15(15.63%) | 0.000 |
16 | SM-LC aggregation† | 15(35.70%) | 2(50.00%) | 9(32.10%) | 0.720a |
17 | M-LC aggregation† | 25(18.25%) | 2(10.00%) | 24(25.00%) | 0.253 |
18 | SM fibrosis† | 6(14.30%) | 0(0.00%) | 2(7.10%) | 0.480a |
19 | Ganglion cells | 18(13.14%) | 1(5.00%) | 5(5.21%) | 0.100 |
20 | Granulation tissue | 14(10.22%) | 2(10.00%) | 5(5.21%) | 0.425 |
21 | Granuloma | 24(17.52%) | 3(15.00%) | 2(2.08%) | 0.001 |
Granulomatous lymphangitis | 33(24.09%) | 1(5.00%) | 0(0.00%) | 0.078b | |
Number of parameters | 6.96 ± 3.73 | 5.1 ± 3.86 | 3.46 ± 3.39 | 0.000 | |