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Table 3 Distribution of values of the biochemical and hematological parameters in the studied groups

From: Anthropometric, biochemical and clinical assessment of malnutrition among Egyptian children with chronic liver diseases: a single institutional cross-sectional study

Serum values (normal values)

Group I (Cases) (n = 69)

Group II (Controls) (n = 50)

P value

Conjugated Bilirubin (μmol /L) (<  3.4 μmol/L) [median, IQR]

70.1 (129.9) (1.7–205.2)

1.71 (0.34) (1.7–3.4)

< 0.001

Total Bilirubin (μmol /L) (<  21 μmol/L) [median, IQR]

111.5 (181.3) (1.7–388.3)

8.55 (3.42) (5.1–13.7)

< 0.001

AST (U/L) (<  1 year (15–60); 1–3 years (20–60); 4–6 years (15–50) [median, IQR]

117 (130.5) (19–831)

29.5 (16.25) (18–48)

< 0.001

ALT (U/L) (13–45) [median, IQR]

72 (96) (14–472)

23 (10) (10–44)

< 0.001

GGT (U/L) [<  1 year boy (5–65); <  1 year girl (5–35); 1–5 years (0–23)] [median, IQR]

261 (531.5) (12–2164)

13 (12.25) (5–32)

< 0.001

ALP (U/L) [<  2 years (150–40);2–10 years (100–320)] [median, IQR]

461 (437.5) (79–1925)

194 (77) (147–403)

< 0.001

Albumin (μmol/L) [4–6 months (2.8–5); 7–12 months (3.2–5.7); 13–24 months (1.9–5); 25–36 months (3.3–5.8); 3–5 years (2.9–5.8)] [mean ± SD]

3.4 ± 0.8 (1.6–5)

4.2 ± 0.7 (3–5.5)

< 0.001

Prothrombin time (seconds) [<  1 year [13 (10.1–15.9); 1–5 years (11 (10.6–11.4)] [mean ± SD]

15.3 ± 3.5 (13–32)

12.9 ± 0.5 (12–13.9)

< 0.001

IGF-1(nmol/L) (2.22–37.13) [median, IQR]

3.14 (1.38) (1.78–5.09)

5.22 (0.99) (4.31–6.93)

< 0.001

25 (OH) D (nmol/L) (42.43–134.7) [mean ± SD]

63 ± 13.25 (33.25–98.5)

59.75 ± 9 (64.75–152.5)

< 0.001

INR [1 (0.96–1.04)] [mean ± SD]

1.2 ± 0.4 (1–3.2)

1

< 0.001

Hemoglobin (g/dl) [6 months-2 years (12); 2–6 years (12.5)]

10.1 ± 0.15 (6.7–14.1)

11.9 ± 1.4 (9.6–14.5)

< 0.001

Total leucocytic count (× 103/μL) [6 months-2 years (8.5 (5–15.5); 2–6 years (8.1 (4.5–13.5)] [mean ± SD]

11.5 ± 4.7 (3.5–25)

10.5 ± 4.1 (4.8–14)

0.229

Platelets (× 103/μL) [mean ± SD] [6 months-6 years (150–350)]

342.3 ± 194.1 (15–964)

279.1 ± 135.5 (190–856)

0.050

  1. ALP Alkaline phosphatase; ALT Alanine aminotransferase; AST Aspartate aminotransferase; GGT Gamma glutamyl transferase, IGF-1 Insulin- like growth factor 1, INR: International normalized ratio; IQR interquartile range; SD standard deviation; 25 (OH) D: 25- hydroxyvitamin D,