Table 3 Clinicopathological characteristics of patients with sarcopenia and intramuscular fat deposition
Variable | Sarcopenia | Intramuscular fat deposition | ||||
|---|---|---|---|---|---|---|
Yes (N = 31) | No (N = 69) | P-value | Yes (N = 65) | No (N = 35) | P-value | |
Age, mean ± SD‡ | 57.64 ± 10.65 | 53.85 ± 11.32 | 0.118 | 56.83 ± 10.83 | 51.68 ± 11.26 | 0.041 |
Gender male, N (%) | 23 (74.19) | 51 (73.91) | 0.976 | 49 (75.38) | 25 (71.43) | 0.667 |
Body mass index (kg/m2), median (IQR)† | 17.30 (16.11–19.85) | 20.32 (19.20–24.13) | < 0.001 | 19.82 (17.63–23.04) | 19.83 (17.85–23.12) | 0.903 |
Viral status, N (%) | 0.415 | 0.166 | ||||
HBV | 21 (67.74) | 37 (53.62) | 42 (64.62) | 16 (45.71) | ||
HCV | 2 (6.45) | 6 (8.70) | 5 (7.69) | 3 (8.57) | ||
HBV + HCV | 0 | 0 | 0 | 0 | ||
None | 8 (25.81) | 26 (37.68) | 18 (27.69) | 16 (45.71) | ||
Child–Pugh class, N (%)†‡ | < 0.001 | < 0.001 | ||||
A | 10 (32.26) | 50 (72.46) | 29 (44.62) | 31 (88.57) | ||
B | 15 (48.39) | 17 (24.64) | 29 (44.62) | 3 (8.57) | ||
C | 6 (19.35) | 2 (2.90) | 7 (10.77) | 1 (2.86) | ||
AST (IU/L), median (IQR) ‡ | 190.0 (85.0–262.5) | 94.0 (47.0–174.0) | 0.274 | 138.0 (71.0–256.0) | 67.0 (36.0–132.5) | 0.031 |
ALT (IU/L), median (IQR) | 61.0 (27.5–82.5) | 40.0 (24.0–77.0) | 0.965 | 46.0 (28.0–82.0) | 33.0 (21.5–69.0) | 0.833 |
Total Bilirubin (mg/dl), median (IQR) | 1.11 (0.68–2.25) | 0.92 (0.5–1.31) | 0.132 | 1.16 (0.55–1.80) | 0.80 (0.47–1.09) | 0.093 |
Albumin (g/dl), median (IQR) ab | 3.06 (2.64–3.48) | 3.41 (2.99–3.91) | 0.010 | 3.13 (2.68–3.60) | 3.55 (3.22–3.94) | 0.004 |
INR, median (IQR) ab | 1.19 (1.08–1.33) | 1.10 (0.99–1.25) | 0.037 | 1.17 (1.07–1.32) | 1.05 (0.99–1.17) | 0.001 |
Platelet count (× 1000/μl), median (IQR) | 270.0 (194.0–297.25) | 276.0 (201.0–328.0) | 0.474 | 270.0 (194.0–317.0) | 283.0 (220.5–321.0) | 0.292 |
CRP, mean (mg/L) ± SDb | 59.56 ± 7.12 | 54.89 ± 6.55 | 0.827 | 71.81 ± 7.50 | 34.61 ± 4.67 | 0.049 |
Creatinine, mean (mg/dl) ± SD | 0.98 ± 0.53 | 0.88 ± 0.36 | 0.251 | 0.94 ± 0,45 | 0.85 ± 0.35 | 0.309 |
Random blood glucose, mean (mg/dl) ± SD | 117.27 ± 39.35 | 121.00 ± 37.97 | 0.661 | 120.65 ± 42.29 | 118.19 ± 29.21 | 0.768 |
Blood sodium, mean (mEq/L) ± SDab | 133.61 ± 5.19 | 135.35 ± 5.07 | 0.131 | 133.66 ± 4.72 | 137.00 ± 5.24 | 0.002 |
Blood potassium, mean (mEq/L) ± SDa | 3.97 ± 1.47 | 3.21 ± 1.79 | 0.035 | 3.56 ± 1.64 | 3.20 ± 1.88 | 0.334 |
BCLC stage, N (%)b | 0.002 | < 0.001 | ||||
A | 1 (3.22) | 6 (8.70) | 1 (1.54) | 6 (17.14) | ||
B | 3 (9.68) | 22 (31.88) | 9 (13.85) | 16 (45.71) | ||
C | 20 (64.52) | 39 (56.52) | 46 (70.77) | 13 (37.14) | ||
D | 7 (22.58) | 2 (2.90) | 9 (13.85) | 0 | ||
AFP level, N (%)b | 0.416 | 0.001 | ||||
< 200 ng/ml | 13 (41.94) | 35 (50.72) | 23 (35.38) | 25 (71.43) | ||
≥ 200 ng/ml | 18 (58.06) | 34 (49.28) | 42 (64.62) | 10 (28.57) | ||