Skip to main content

Table 5 Predictors of acute kidney injury within 90 days of initial liver transplant evaluation visit on univariate and multivariate Cox Proportional Hazard Regression analysis. The unadjusted hazard ratio for NSBB use and acute kidney injury between 90 and 365 days of initial evaluation was 0.97, 95% confidence interval 0.4 to 2.7, p = 0.9

From: Non-selective beta blocker use is associated with improved short-term survival in patients with cirrhosis referred for liver transplantation

 

Univariate

Multivariate

Hazard Ratio

(95% CI)

P value

Hazard Ratio

(95% CI)

P value

MELD

1.17 (1.08–1.29)

<.001

1.19 (1.07–1.3)

.001

Mean arterial pressure (mmHg)

0.96 (.92–1.00)

.08

  

NSBB

3.4 (1.2–9.8)

.02

  

Child Pugh Score

1.44 (1.13–1.83)

.003

  
  1. Factors not predictive of acute kidney injury within 90 days included; NSSB use, age, gender, body mass index, race, etiology of liver disease (hepatitis C, alcoholic or non-alcoholic fatty liver disease), diabetes mellitus, hypertension and serum albumin and sodium
  2. When analysis was performed for prediction of ≥ stage 2 acute kidney injury within 90 days, the unadjusted hazard ratio for NSBB use was 4.5, 95% CI 0.9–22, p = 0.06, and the adjusted hazard ratio was 0.7, 95% CI 0.08–6.3, p = 0.7 on (adjusted for age, MELD, mean arterial pressure and Childs Pugh score)
  3. Abbreviations: MELD model for end-stage liver disease, NSBB non-selective beta blockers
Back to article page

BMC Gastroenterology

ISSN: 1471-230X

Contact us