Fig. 2
From: A PTPN11 mutation in a woman with Noonan syndrome and protein-losing enteropathy
a shows the pedigree of the patient’s family. Patients are represented in black and the arrow represents the proband, which is the patient discussed in this article. b shows the Sanger sequencing of the PTPN11 gene in the family. A missense mutation was found in PTPN11 (c.A922G p.N308D) of the patient (II4), which was inherited by her daughter (III6). The patient’s father died of acute cerebrovascular disease before genetic testing