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Table 1 Baseline demographic and clinical characteristics of the 340 patients evaluated for liver transplantation for complications of cirrhosis. Data are shown as mean ± standard deviation or percentage unless otherwise specified. Patients who died within 90-days without LT and those who survived at least 90-days without LT are compared (8 patients underwent LT within 90-days and were excluded)

From: Extra-hepatic comorbidity burden significantly increases 90-day mortality in patients with cirrhosis and high model for endstage liver disease

Demographic and clinical characteristics

Patients assessed

N = 340

Patients who died within 90 days

n = 33

Patients who survived 90-days without LT

n = 297

p-value

Age

56 ± 11

57 ± 9

56 ± 9

0.5

Gender (male) (%)

63

21

40

0.04

Race (%)

 White

90

85

91

0.6

 Black

5

9

4

 Hispanic

3

6

3

 Asian

1

None

1

 Other

1

None

1

Body mass index

30 ± 7

30 ± 8

30 ± 6

0.7

Etiology of liver disease (%)

 Alcohol

19

12

20

0.4

 Alcohol and viral

16

24

16

 Viral

32

39

31

 Autoimmune

8

None

8

 Fatty liver

21

21

21

 Cryptogenic

2

3

2

MELD-Na

17.2 ± 6.6

25.1 ± 7.3

16.2 ± 5.8

< 0.001

Hepatocellular carcinoma (%)

24

30

23

0.4

CCI (mean)

1 ± 1.2

1.4 ± 1.2

1 ± 1.2

0.09

 (median (IQR))

1 (0,1)

1 (0, 2)

1 (0,1)

CCI category (%)

 CCI = 0

44

30

46

0.07

 CCI = 1–2

44

52

43

 CCI > 2

12

18

110.

CIRCOM (mean)

0.8 ± 1.2

1.6 ± 1.4

0. ± 1.1

0.001

 (median (IQR))

0 (0,1)

1 (0, 3)

0 (0,1)

  1. Abbreviations: CCI Charlson Comorbidity Index (excluding liver disease and liver cancer), IQR interquartile range, LT liver transplantation, MELD-Na Model for End-stage Liver Disease with sodium modification