From: Elobixibat alleviates chronic constipation in hemodialysis patients: a questionnaire-based study
 | Baseline Mean ± SD, median [IQR] | Week 4 Mean ± SD, median [IQR] | P value | Bayes factor |
---|---|---|---|---|
PAC-QOL | ||||
 Global score | 1.83 ± 0.67 | 1.17 ± 0.56 | < 0.001 | < 0.001 |
1.93 [1.29, 2.36] | 1.14 [0.71, 1.57] | |||
 Physical discomfort | 1.94 ± 0.79 | 0.97 ± 0.72 | < 0.001 | < 0.001 |
2.00 [1.25, 2.50] | 1.00 [0.50, 1.50] | |||
 Psychosocial discomfort | 1.16 ± 0.93 | 0.63 ± 0.58 | < 0.001 | 0.010 |
0.88 [0.25, 2.00] | 0.50 [0.00, 1.00] | |||
 Worries and concerns | 1.84 ± 0.73 | 1.27 ± 0.59 | < 0.001 | 0.001 |
2.00 [1.09, 2.45] | 1.18 [0.82, 1.91] | |||
 Satisfaction | 2.79 ± 0.61 | 1.98 ± 0.77 | < 0.001 | 0.002 |
2.80 [2.40, 3.40] | 2.00 [1.60, 2.60] | |||
 Weekly SBM | 2.6 ± 1.2 | 4.1 ± 2.1 | < 0.001 | < 0.001 |
2 [2, 3] | 4 [2, 5] | |||
 Bristol Stool Form Scale score | 1.9 ± 0.8 | 3.6 ± 0.7 | < 0.001 | 0.007 |
2 [1, 2] | 4 [3, 4] |