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Table 3 PAC-QOL, SBM, and Bayes factor at baseline and week 4

From: Elobixibat alleviates chronic constipation in hemodialysis patients: a questionnaire-based study

 

Baseline

Mean ± SD, median [IQR]

Week 4

Mean ± SD, median [IQR]

P value

Bayes factor

PAC-QOL

 Global score

1.83 ± 0.67

1.17 ± 0.56

< 0.001

< 0.001

1.93 [1.29, 2.36]

1.14 [0.71, 1.57]

 Physical discomfort

1.94 ± 0.79

0.97 ± 0.72

< 0.001

< 0.001

2.00 [1.25, 2.50]

1.00 [0.50, 1.50]

 Psychosocial discomfort

1.16 ± 0.93

0.63 ± 0.58

< 0.001

0.010

0.88 [0.25, 2.00]

0.50 [0.00, 1.00]

 Worries and concerns

1.84 ± 0.73

1.27 ± 0.59

< 0.001

0.001

2.00 [1.09, 2.45]

1.18 [0.82, 1.91]

 Satisfaction

2.79 ± 0.61

1.98 ± 0.77

< 0.001

0.002

2.80 [2.40, 3.40]

2.00 [1.60, 2.60]

 Weekly SBM

2.6 ± 1.2

4.1 ± 2.1

< 0.001

< 0.001

2 [2, 3]

4 [2, 5]

 Bristol Stool Form Scale score

1.9 ± 0.8

3.6 ± 0.7

< 0.001

0.007

2 [1, 2]

4 [3, 4]

  1. PAC-QOL Patients Assessment of Constipation-Quality of Life, SBM spontaneous bowel movement