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Table 5 PAC-QOL, SBM, and Bayes factor at baseline and week 4 in patients taking 2 or 3 laxatives (N = 14)

From: Elobixibat alleviates chronic constipation in hemodialysis patients: a questionnaire-based study

 

Baseline

Mean ± SD, median [IQR]

Week 4

Mean ± SD, median [IQR]

P value

Bayes factor

PAC-QOL

 Global score

1.97 ± 0.68

1.21 ± 0.67

0.002

0.009

2.00 [1.44, 2.52]

1.41 [0.43, 1.69]

 Physical discomfort

2.07 ± 0.88

0.76 ± 0.64

0.002

0.020

2.00 [1.25, 2.75]

0.82 [0.00, 1.50]

 Psychosocial discomfort

1.36 ± 0.93

0.63 ± 0.58

0.012

0.174

1.57 [0.56, 2.13]

0.50 [0.00, 1.00]

 Worries and concerns

1.95 ± 0.71

1.30 ± 0.65

0.002

0.010

2.09 [1.29, 2.57]

1.45 [0.64, 1.96]

 Satisfaction

2.90 ± 0.64

1.87 ± 0.93

0.004

0.056

3.00 [2.35, 3.45]

2.00 [1.10, 2.65]

 Weekly SBM

2.3 ± 1.0

3.2 ± 1.5

0.027

0.363

2 [2, 3]

3 [2, 4]

 Bristol Stool Form Scale score

1.8 ± 0.8

3.6 ± 0.8

0.002

0.001

2 [1, 2]

4 [3, 4]