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Table 6 Likelihood ratio for positive result (LR+), likelihood ratio for negative result (LR-) and its inverse (1/LR-), posttest odds ratio (posttest OR), and probability following tests (posttest P) of Crohn’s disease activity for each noninvasive marker exam and their respective cut-offs

From: Faecal calprotectin is the biomarker that best distinguishes remission from different degrees of endoscopic activity in Crohn’s disease

 

LR+

LR-

1/LR-

Posttest OR

Posttest P

fCal≥155 mcg/g

1.73

0.08

11.69

3.36

0.77

fCal≥199 mcg/g

1.74

0.20

5.01

3.38

0.77

fCal≥246 mcg/g

1.83

0.22

4.49

3.56

0.78

fCal≥273 mcg/g

1.95

0.24

4.12

3.77

0.79

fCal≥1009 mcg/g

3.50

0.56

1.77

6.80

0.87

fCal≥ 1473 mcg/g

5.45

0.64

1.55

10.58

0.91

CRP ≥ 6.7 mg/L

2.25

0.38

2.66

4.36

0.81

Pla ≥ 292,500/mm3

1.96

0.51

1.92

3.80

0.79

  1. fCal Faecal calprotectin, CRP Serum C-reactive protein, Pla Platelet count, LR+ Likelihood ratio for positive result, LR- Likelihood ratio for negative result, 1/LR- Likelihood ratio in patients in remission, OR odds ratio, Posttest P Posttest probability of CD activity