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Table 5 Mean serum concentrations of biochemical parameters in IBS-D patients with low (LS) and high scores (HS) of somatization (Subscale of SCL-90-R)

From: Somatization in patients with predominant diarrhoea irritable bowel syndrome: the role of the intestinal barrier function and integrity

 

LS

(n = 19)

HS

(n = 28)

P

IFABP-2 (ng/ml)

3.76 ± 5.94

2.97 ± 2.96

0.19

DAO (ng/ml)

36.10 ± 5.12

35.53 ± 4.32

0.57

Faecal Zonulin (ng/ml)

127.0 ± 67.0

180.0 ± 90.0

0.035

Serum Zonulin (ng/ml)

29.0 ± 7.1

29.0 ± 5.5

0.81

IL-6 (pg/ml)

5.76 ± 1.61

6.83 ± 7.52

0.97

IL-8 (pg/ml)

3.71 ± 0,60

5.17 ± 2.88

0.007

IL-10 (pg/ml)

3.44 ± 0.78

2.94 ± 0.28

0.02

TNF-α(pg/ml)

3.92 ± 1.22

3.57 ± 0.50

0.14

  1. Data are expressed as means ± SD. P-value was determined by Mann–Whitney rank-sum test; differences were considered significant at P < 0.05. LS, Low somatization level; cut-off score < 63. HS, High somatization level; cut-off score ≥ 63