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Table 5 Association between DAL-1 (rs9953490) genotypes and clinicopathologic features of GC

From: The rs9953490 polymorphism of DAL-1 gene is associated with gastric cancer risk in the Han population in Northeast China

Variables

rs9953490

OR (95% CI)

P

Adjusted OR

(95% CI)a

Pa

TA + AA(n)

TT

(n)

Tumor size(cm)

 < 5

21

140

1

 

1

 

 ≥ 5

21

92

 

0.21

1.52 (0.77–2.98)

0.224

Neoplasia location

 Non-cardia

36

202

1

 

1

 

 Cardia

6

30

 

0.811

1.14 (0.43–2.99)

0.796

Invasion depth

 T1–T2

14

76

1

 

1

 

 T3-T4

28

156

 

0.942

0.94 (0.46–1.91)

0.863

Lymph metastasis

 N0

15

98

1

 

1

 

 N1

9

63

 

0.879

1.32 (0.51–3.41)

0.561

 N2

10

54

 

0.666

1.49 (0.6–3.71)

0.388

 N3

8

17

3.07(1.17–8.10)

0.023

4.56 (1.49–13.98)

0.008*

TNM stage

 I–II

23

167

1

 

1

 

 III

19

65

2.12(1.09–4.12)

0.026

2.33 (1.16–4.67)

0.017*

Lauren’s classification

 Intestinal

32

171

1

 

1

 

 Diffuse

10

61

 

0.735

0.87 (0.38–1.99)

0.738

  1. CI confidence interval, OR odd ratio
  2. *Indicates statistically significant data
  3. aAdjusted for age, gender, smoking status, pack-years and drinking status