From: Helicobacter pylori infection in Iran: demographic, endoscopic and pathological factors
Demographic and clinical data | Total N = 233 n (%) | H. pylori positive N = 109 n (%) | H. pylori negative N = 124 n (%) | OR crude (95% CI) | P Value | OR adjusted (95% CI) | P value |
---|---|---|---|---|---|---|---|
Gender | |||||||
 Men | 125 (53.6) | 55 (44.0) | 70 (56.0) | 0.78 (0.46–1.31) | 0.430 | 0.51 (0.20–1.33) | 0.174 |
 Women | 108 (46.4) | 54 (50.0) | 54 (50.0) | Ref |  | Ref |  |
Age group | |||||||
 < 35 | 57 (24.5) | 21 (36.8) | 36 (63.2) | 1.25 (0.80–2.87) | 0.196 | 0.72 (0.20–2.54) | 0.612 |
 35–45 | 42 (18.0) | 25 (59.5) | 17 (40.5) | 0.60 (0.29–1.21) | 0.159 | 2.47 (0.81–7.53) | 0.111 |
 > 45 | 134 (57.5) | 63 (47.0) | 71 (53.0) | Ref | – | Ref | – |
BMI | |||||||
 < 18.5 | 3 (1.3) | 0 (0.0) | 3 (100.0) | N/A | – | N/A | – |
 18.5–24.9 | 35 (15.0) | 17 (48.6) | 18 (51.4) | 1.52 (0.57–4.07) | 0.398 | 1.76 (0.44–7.00) | 0.420 |
 25–29.9 | 145 (62.2) | 69 (47.6) | 76 (52.4) | 1.32 (0.57–3.04) | 0.504 | 1.82 (0.61–5.35) | 0.277 |
 > 30 | 50 (21.5) | 23 (46.0) | 27 (54.0) | Ref | – | Ref | - |
Number of family member | |||||||
 < 3 | 93 (39.9) | 37 (39.8) | 56 (60.2) | 0.62 (0.36–1.06) | 0.084 | 0.74 (0.35–1.56) | 0.428 |
 > 3 | 140 (60.1) | 72 (51.4) | 68 (48.6) | Ref |  | Ref | – |
Smoking | |||||||
 Yes | 79 (33.9) | 33 (41.8) | 46 (58.2) | 0.73 (0.42–1.27) | 0.332 | 0.68 (0.29–1.62) | 0.395 |
 No | 154 (66.1) | 76 (49.4) | 78 (50.6) | Ref |  | Ref | – |
Alcohol drink | |||||||
 Yes | 32 (13.7) | 16 (50.0) | 16 (50.0) | 1.16 (0.55–2.45) | 0.707 | 1.75 (0.60–5.08) | 0.301 |
 No | 201 (86.3) | 93 (46.3) | 108 (53.7) | Ref |  | Ref | – |
Education | |||||||
 Illiterate | 10 (4.3) | 3 (30.0) | 7 (70.0) | 0.45 (0.11–1.87) | 0.277 | 0.13 (0.02–0.84) | 0.033 |
 Under diploma | 47 (20.2) | 24 (51.1) | 23 (48.9) | 1.11 (0.55–2.24) | 0.765 | 0.43(0.12–1.58) | 0.209 |
 Diploma | 83 (35.6) | 37 (44.6) | 46 (55.4) | 0.85 (0.47–1.55) | 0.613 | 0.47 (0.17–1.28) | 0.141 |
Upper graduated | 93 (39.9) | 45 (48.4) | 48 (51.6) | Ref | – | Ref | – |
Marital status | |||||||
 Single | 44 (18.9) | 12 (27.3) | 32 (72.7) | 0.35 (0.17–0.73) | 0.01 | 0.38 (0.12–1.13) | 0.082 |
 Married | 189 (81.1) | 97 (51.1) | 92 (48.9) | Ref |  | Ref | – |
Occupation | |||||||
 Unemployed | 56 (24.0) | 32 (57.1) | 24 (42.9) | 2.24 (1.08–4.62) | 0.029 | 6.70 (2.22–20.23) | 0.001 |
 Housekeeping | 71 (30.5) | 32 (45.1) | 39 (54.9) | 1.37 (0.69–2.72) | 0.356 | 1.03 (0.30–3.49) | 0.951 |
 Employee | 39 (16.7) | 20 (51.3) | 19 (48.7) | 1.76 (0.79–3.93) | 0.162 | 0.90 (0.28–2.80) | 0.856 |
 Self employed | 67 (28.8) | 25 (37.3) | 42 (62.7) | Ref | – | Ref | – |
Drinking water source | |||||||
 River | 1 (0.4) | 1 (100.0) | 0 (0.0) | N/A | – | N/A | – |
 Tap | 153 (65.7) | 68 (44.4) | 85 (55.6) | 0.85 (0.39–1.84) | 0.688 | 0.97 (0.36–2.57) | 0.957 |
 Mineral | 48 (20.6) | 25 (52.1) | 23 (47.9) | 1.15 (0.47–2.86) | 0.748 | 1.07 (0.33–3.46) | 0.909 |
 Tap and Mineral | 31 (13.3) | 15 (48.4) | 16 (51.6) | Ref | – | Ref | – |
Family history of gastrointestinal cancer | |||||||
 Yes | 44 (18.9) | 30 (68.2) | 14 (31.8) | 2.98 (1.48–5.99) | 0.002 | 3.52 (1.48–8.35) | 0.004 |
 No | 189 (81.9) | 79 (41.8) | 110 (58.2) | Ref |  | Ref | – |
Gastrointestinal sign and symptomsa | |||||||
 Epigastric pain | 157 (67.4) | 85 (54.1) | 72 (45.9) | 2.70 (1.50- 4.83) | 0.001 | 4.67 (1.92–11.34) | 0.001 |
 Heartburn | 107 (45.9) | 24 (31.6) | 52 (68.4) | 1.06 (0.63–1.78) | 0.895 | 1.83 (0.89–3.75) | 0.009 |
 Reflux | 76 (32.6) | 34 (44.7) | 42 (55.3) | 0.88 (0.51–1.53) | 0.677 | 1.35 (0.61–2.99) | 0.458 |
 Weight loss | 55 (23.6) | 34 (61.8) | 21 (38.2) | 2.22 (1.19- 4.13) | 0.013 | 3.38 (1.34–8.49) | 0.009 |
 Decreased appetite | 64 (27.5) | 35 (54.7) | 29 (45.3) | 1.54 (0.86–2.76) | 0.144 | 1.62 (0.69–3.78) | 0.262 |
 Early satiety | 17 (7.3) | 8 (47.1) | 9 (52.9) | 1.01 (0.37–2.72) | 0.981 | 1.73 (0.44–6.77) | 0.425 |
 The presence of blood in the stool | 9 (3.9) | 2 (22.2) | 7 (77.8) | 0.31 (0.06–1.55) | 0.181 | 0.66 (0.11–3.88) | 0.654 |
 Iron deficiency anemia | 27 (11.6) | 15 (55.6) | 12 (44.4) | 1.48 (0.66–3.33) | 0.413 | 1.62 (0.55–4.79) | 0.378 |