Table 2 Differences in life expectancy at 65 years comparing medications used to treat seniors with inflammatory bowel disease
Mesalamine | Immunomodulator monotherapy | Biologic monotherapy | Combination therapy | Systemic steroids | |
|---|---|---|---|---|---|
No therapy | |||||
Females | − 3.4 (− 3.9, − 2.9) | 3.2 (2.4, 4.1) | 2.3 (0.4, 4.2) | − 1.8 (− 4.5, 0.9) | 7.1 (6.3, 7.8) |
Males | − 2.5 (− 3.0, − 2.1) | 3.3 (2.5, 4.0) | 2.5 (0.7, 4.3) | 0.4 (− 2.2, 3.1) | 6.8 (6.2, 7.5) |
Mesalamine | |||||
Females | 6.7 (5.8, 7.5) | 5.7 (3.8, 7.6) | 1.6 (− 1.1, 4.3) | 10.5 (9.7, 11.3) | |
Males | 5.8 (5.0, 6.6) | 5.0 (3.2, 6.8) | 3.0 (0.3, 5.6) | 9.4 (8.7, 10.0) | |
Immunomodulator monotherapy | |||||
Females | − 0.9 (− 3.0, 1.1) | − 5.1 (− 7.8, − 2.3) | 3.8 (2.8, 4.9) | ||
Males | − 0.8 (− 2.7, 1.1) | − 2.8 (− 5.5, − 0.1) | 3.6 (2.7, 4.5) | ||
Biologic monotherapy | |||||
Females | − 4.1 (− 7.4, − 0.9) | 4.8 (2.8, 6.7) | |||
Males | − 2.1 (− 5.2, 1.1) | 4.3 (2.5, 6.2) | |||
Combination therapy | |||||
Females | 8.9 (6.1, 11.6) | ||||
Males | 6.4 (3.7, 9.1) | ||||