Laboratory dataset | DAD | |||||
---|---|---|---|---|---|---|
IBD patients with CDI (n = 108) | Matched IBD patients without CDI (n = 531) | p-value | IBD patients with CDI (n = 110) | Matched IBD patients without CDI (n = 539) | p-value | |
Age median (IQR) | 55.5(34–75) | 55 (34–75) | 60 (40–75) | 59 (40–74) | ||
% CD | 51 | 51 | 46 | 47 | ||
% Male | 44 | 44 | 47 | 48 | ||
Use 1 year prior | ||||||
5-ASA use (%) | 47.2 | 37.9 | 0.084 | 51.8 | 39.2 | 0.015 |
Thiopurine use (%) | 19.4 | 16.4 | 0.48 | 16.4 | 13.5 | 0.45 |
Anti-TNF use (%) | 7.4 | 8.7 | 0.85 | 10.9 | 8.0 | 0.35 |
Corticosteroid use (%) | 45.4 | 22.6 | < 0.001 | 40.9 | 22.3 | < 0.001 |
Use 3 month prior | ||||||
Any antibiotic use (%) | 50.0 | 23.5 | < 0.001 | 50.9 | 19.8 | < 0.001 |
Ciprofloxacin use (%) | 16.7 | 6.4 | 0.002 | 16.4 | 5.2 | < 0.001 |
Metronidazole use (%) | 17.6 | 4.7 | < 0.001 | 16.4 | 3.3 | < 0.001 |
Clindamycin use (%) | Data too sparse to report N < 6 | 0.031 | Data too sparse to report N < 6 | 0.016 | ||
Hospitalization in the prior year (%) | 62.0 | 31.1 | < 0.001 | 63.6 | 31.5 | < 0.001 |
Surgery (%) | 23.2 | 23.9 | 0.90 | 20.0 | 25.1 | 0.28 |
Charlson Comorbidity index score (%) | 0.002 | 0.004 | ||||
0 | 49.1 | 61.6 | 42.7 | 59.0 | ||
1 | 16.7 | 19.4 | 20.0 | 19.1 | ||
2 | 21.3 | 9.6 | 17.3 | 9.5 | ||
3+ | 13.0 | 9.4 | 20.0 | 12.4 | ||
Ambulatory care (%) | < 0.001 | < 0.001 | ||||
Lowest quartile | 11.1 | 29.8 | 10.0 | 30.2 | ||
2nd quartile | 15.7 | 25.8 | 14.6 | 25.1 | ||
3rd quartile | 34.3 | 22.2 | 34.6 | 23.4 | ||
Highest quartile | 38.9 | 22.2 | 40.9 | 21.3 |