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Table 3 EQ-5D-3L mean score comparisons between groups

From: The impact of treatment with bile acid sequestrants on quality of life in patients with bile acid diarrhoea

Field

Visit

Control group

BAD

PC

CD

p Value

Mobility

(MOB)

Before Treatment

1.50

(1.22–1.78)

1.30

(1.10–1.51)

1.36

(1.02–1.70)

1.18

(0.91–1.45)

0.39

After treatment

 

1.30

(1.06–1.55)

1.55

(1.19–1.89)

1.00

(1.00–1.00)

*0.04

p value

p = 1.0

p = 0.34

p = 0.17

 

Self-care

(SC)

Before treatment

1.25

(0.99–1.51)

1.04

(0.95–1.13)

1.08

(0.90–1.27)

1.09

(0.89–1.29)

0.36

After treatment

 

1.00

(1.00–1.00)

1.17

(0.91–1.41)

1.00

(1.00–1.00)

0.05

p value

p = 0.39

p = 0.34

p = 0.34

 

Activity

(ACT)

Before treatment

1.67

(1.40–1.94)

2.04

(1.76–2.24)

1.50

(1.07–1.93)

1.45

(1.10–1.81)

*0.04

After treatment

 

1.52

(1.20–1.80)

1.67

(1.35–1.98)

1.45

(1.10–1.81)

0.65

p value

* p = 0.002

p = 0.44

p = 1.0

 

Pain and Discomfort

(PD)

Before treatment

1.96

(1.72–2.19)

1.96

(1.75–2.16)

1.92

(1.59–2.24)

2.00

(1.47–2.52)

0.99

After treatment

 

1.78

(1.52–2.04)

2.00

(1.62–2.38)

1.55

(1.08–2.01)

0.23

p value

p = 0.16

p = 0.59

p = 0.1

 

Anxiety and Depression

(AD)

Before treatment

1.79

(1.49–2.10)

1.87

(1.60–2.14)

1.67

(1.35–1.98)

1.91

(1.71–2.11)

0.75

After treatment

 

1.61

(1.36–1.86)

1.92

(1.41–2.42)

1.64

(1.30–1.98)

0.37

p value

p = 0.06

p = 0.19

p = 0.19

 

Visual Analogue Scale

(VAS)

Before treatment

66.68

(55.89–77.47)

59.23

(48.70–69.85)

54.67

(39.59–69.75)

64.09

(46.17–82.01)

0.53

After treatment

 

63.14

(54.14–72.14)

59.33

(41.82–76.85)

71.64

(58.25–85.02)

0.41

p value

p = 0.48

p = 0.39

p = 0.26

 
  1. BAD: Bile acid diarrhoea, PC: post-cholecystectomy, CD: terminal ileal resected Crohn’s Disease. 95%CI is represented within parenthesis. p Values on the right-hand column indicate comparison of mean scores between the groups at that specific moment in time. The p values in each row indicate comparison of mean scores between each group before and after treatment. * denotes p < 0.05