Characteristic | Univariable analysis | Multivariable analysis | ||||
---|---|---|---|---|---|---|
HR | 95% CI | P value | HR | 95% CI | P value | |
Age | ||||||
<40 | Reference | Â | Â | Reference | Â | Â |
40-59 | 1.122 | 0.916–1.375 | 0.265 | 1.311 | 1.067–1.610 | 0.010 |
60-79 | 2.419 | 1.994–2.934 | < 0.001 | 2.819 | 2.314–3.433 | < 0.001 |
≥80 | 6.081 | 5.001–7.394 | < 0.001 | 6.573 | 5.364–8.053 | < 0.001 |
Sex | ||||||
Male | Reference | Â | Â | Reference | Â | Â |
Female | 0.889 | 0.840–0.941 | < 0.001 | 0.755 | 0.710–0.803 | < 0.001 |
Race | ||||||
White | Reference | Â | Â | Reference | Â | Â |
Black | 0.991 | 0.899–1.092 | 0.849 | 1.177 | 1.065–1.301 | 0.001 |
Other | 0.838 | 0.759–0.926 | 0.001 | 0.956 | 0.864–1.057 | 0.380 |
Marital status | ||||||
Married | Reference | Â | Â | Reference | Â | Â |
Separated/Divorced | 1.187 | 1.072–1.315 | 0.001 | 1.295 | 1.168–1.436 | < 0.001 |
Widowed | 2.227 | 1.055–1.257 | < 0.001 | 1.585 | 1.465–1.714 | < 0.001 |
Single | 1.152 | 1.055–1.257 | 0.002 | 1.387 | 1.267–1.518 | < 0.001 |
Primary tumor sites | ||||||
Cardiac/Fundus | Reference | Â | Â | Reference | Â | Â |
Body | 0.987 | 0.881–1.105 | 0.987 | – | – | – |
Antrum/Pylorus | 0.930 | 0.836–1.035 | 0.930 | – | – | – |
Lesser/Greater curvature | 1.003 | 0.889–1.132 | 0.955 | – | – | – |
Other | 1.058 | 0.968–1.156 | 0.212 | – | – | – |
Histologic subtype | 48 | Â | Â | Â | Â | Â |
DLBCL | Reference | Â | Â | Reference | Â | Â |
MALT | 0.529 | 0.497–0.563 | < 0.001 | 0.534 | 0.495–0.575 | < 0.001 |
Other B cell lymphoma | 1.001 | 0.889–1.128 | 0.986 | 0.888 | 0.786–1.003 | 0.055 |
T/NK cell lymphoma | 1.721 | 1.389–2.132 | < 0.001 | 1.876 | 1.511–2.329 | < 0.001 |
Other NHL | 1.017 | 0.886–1.168 | 0.810 | 0.977 | 0.850–1.122 | 0.738 |
HL | 1.351 | 0.766–2.383 | 0.298 | 1.172 | 0.663–2.072 | 0.584 |
NOS | 1.050 | 0.883–1.249 | 0.582 | 0.975 | 0.818–1.162 | 0.777 |
Stage | ||||||
stage I | Reference | Â | Â | Reference | Â | Â |
stage II | 1.241 | 1.144–1.347 | < 0.001 | 1.244 | 1.143–1.354 | < 0.001 |
stage III | 1.610 | 1.435–1.807 | < 0.001 | 1.484 | 1.316–1.672 | < 0.001 |
stage IV | 1.850 | 1.722–1.988 | < 0.001 | 1.742 | 1.611–1.884 | < 0.001 |
Surgery | ||||||
Yes | Reference | Â | Â | Reference | Â | Â |
No/Unknown | 0.934 | 0.854–1.021 | 0.131 | – | – | – |
Radiotherapy | ||||||
Yes | Reference | Â | Â | Reference | Â | Â |
No/Unknown | 1.632 | 1.518–1.755 | < 0.001 | 1.297 | 1.204–1.396 | < 0.001 |
Chemotherapy | ||||||
Yes | Reference | Â | Â | Reference | Â | Â |
No/Unknown | 0.860 | 0.813–0.911 | < 0.001 | 1.310 | 1.221–1.405 | < 0.001 |