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Table 2 Cox proportional hazard regression analysis of OS in patients with primary gastric lymphoma in the training cohort (n=8898)

From: A dynamic predictive nomogram of long-term survival in primary gastric lymphoma: a retrospective study

Characteristic

Univariable analysis

Multivariable analysis

HR

95% CI

P value

HR

95% CI

P value

Age

<40

Reference

  

Reference

  

40-59

1.122

0.916–1.375

0.265

1.311

1.067–1.610

0.010

60-79

2.419

1.994–2.934

< 0.001

2.819

2.314–3.433

< 0.001

≥80

6.081

5.001–7.394

< 0.001

6.573

5.364–8.053

< 0.001

Sex

Male

Reference

  

Reference

  

Female

0.889

0.840–0.941

< 0.001

0.755

0.710–0.803

< 0.001

Race

White

Reference

  

Reference

  

Black

0.991

0.899–1.092

0.849

1.177

1.065–1.301

0.001

Other

0.838

0.759–0.926

0.001

0.956

0.864–1.057

0.380

Marital status

Married

Reference

  

Reference

  

Separated/Divorced

1.187

1.072–1.315

0.001

1.295

1.168–1.436

< 0.001

Widowed

2.227

1.055–1.257

< 0.001

1.585

1.465–1.714

< 0.001

Single

1.152

1.055–1.257

0.002

1.387

1.267–1.518

< 0.001

Primary tumor sites

Cardiac/Fundus

Reference

  

Reference

  

Body

0.987

0.881–1.105

0.987

–

–

–

Antrum/Pylorus

0.930

0.836–1.035

0.930

–

–

–

Lesser/Greater curvature

1.003

0.889–1.132

0.955

–

–

–

Other

1.058

0.968–1.156

0.212

–

–

–

Histologic subtype

48

     

DLBCL

Reference

  

Reference

  

MALT

0.529

0.497–0.563

< 0.001

0.534

0.495–0.575

< 0.001

Other B cell lymphoma

1.001

0.889–1.128

0.986

0.888

0.786–1.003

0.055

T/NK cell lymphoma

1.721

1.389–2.132

< 0.001

1.876

1.511–2.329

< 0.001

Other NHL

1.017

0.886–1.168

0.810

0.977

0.850–1.122

0.738

HL

1.351

0.766–2.383

0.298

1.172

0.663–2.072

0.584

NOS

1.050

0.883–1.249

0.582

0.975

0.818–1.162

0.777

Stage

stage I

Reference

  

Reference

  

stage II

1.241

1.144–1.347

< 0.001

1.244

1.143–1.354

< 0.001

stage III

1.610

1.435–1.807

< 0.001

1.484

1.316–1.672

< 0.001

stage IV

1.850

1.722–1.988

< 0.001

1.742

1.611–1.884

< 0.001

Surgery

Yes

Reference

  

Reference

  

No/Unknown

0.934

0.854–1.021

0.131

–

–

–

Radiotherapy

Yes

Reference

  

Reference

  

No/Unknown

1.632

1.518–1.755

< 0.001

1.297

1.204–1.396

< 0.001

Chemotherapy

Yes

Reference

  

Reference

  

No/Unknown

0.860

0.813–0.911

< 0.001

1.310

1.221–1.405

< 0.001

  1. The bold numbers indicate that the variables have statistical differences (P < 0.05)