Clinicopathological features | Univariate analysis | Â | Multivariate analysis | Â |
---|---|---|---|---|
HR (95% CI) | P value | HR (95% CI) | P value | |
Gender | ||||
 Female | Reference |  |  |  |
 Male | 0(0-Inf) | 0.998 |  |  |
Age | 0.961(0.904–1.02) | 0.192 |  |  |
BMI | 0.763(0.641–0.909) | 0.002 | 0.884(0.684–1.142) | 0.346 |
Hypertension | ||||
 Yes | 0.363(0.084–1.572) | 0.176 |  |  |
DM | ||||
 Yes | 1.282(0.428–3.839) | 0.657 |  |  |
TB | ||||
 Yes | 0.824(0.109–6.21) | 0.851 |  |  |
Smoking | ||||
 Yes | 0.177(0.024–1.325) | 0.092 |  |  |
Alcohol abuse | ||||
 Yes | 0.399(0.053–2.991) | 0.371 |  |  |
Hyperlipidemia | ||||
 Yes | 0.805(0.235–2.753) | 0.729 |  |  |
Duration of HIV infection | 1.003(0.992–1.015) | 0.586 |  |  |
Duration of HIV treatment | 1.003(0.991–1.016) | 0.58 |  |  |
Tumor Location | ||||
 Upper | Reference |  |  |  |
 Middle | 0.635(0.208–1.935) | 0.424 |  |  |
 Lower | 1.14(0.208–6.247) | 0.88 |  |  |
Histology | ||||
 Signet ring cell | 3.939(1.578–9.836) | 0.003 | 42.638(6.245–291.092) |  < 0.001 |
R0 rescetion | ||||
 No | 4.245(1.382–13.038) | 0.012 | 136.565(8.048–2317.405) |  < 0.001 |
Her2 status | ||||
 0 | Reference |  |  |  |
 1 +  | 0.806(0.302–2.149) | 0.667 |  |  |
 2 +  | 0.563(0.126–2.521) | 0.453 |  |  |
AJCC stage | ||||
 I-II | Reference |  | Reference |  |
 III-IV | 6.297(1.96–20.228) | 0.002 | 0.766(0.135–4.341) | 0.764 |
ALB (g/L) | ||||
 > 38.1 | Reference |  | Reference |  |
 ≤ 38.1 | 4.041(1.553–10.515) | 0.004 | 3.73(0.309–45.103) | 0.301 |
CD8 count (per ul) | ||||
 > 661 | Reference |  |  |  |
 ≤ 661 | 0.741(0.302–1.822) | 0.514 |  |  |
CD4 count (per ul) | ||||
 > 348 | Reference |  |  |  |
 ≤ 348 | 2.667(0.957–7.436) | 0.061 |  |  |
CD4/CD8 | ||||
 > 0.71 | Reference |  |  |  |
 ≤ 0.71 | 1.52(0.581–3.978) | 0.394 |  |  |
NLR | ||||
 > 3.9 | Reference |  | Reference |  |
 ≤ 3.9 | 0.346(0.137–0.873) | 0.025 | 0.109(0.008–1.56) | 0.103 |
LMR | ||||
 > 6.5 | Reference |  |  |  |
 ≤ 6.5 | 3.538(0.472–26.497) | 0.219 |  |  |
PLR | ||||
 > 199.0 | Reference |  | Reference |  |
 ≤ 199.0 | 0.298(0.123–0.723) | 0.007 | 0.027(0.004–0.201) |  < 0.001 |
PNI | ||||
 > 43.4 | Reference |  | Reference |  |
 ≤ 43.4 | 3.129(1.265–7.737) | 0.014 | 0.756(0.057–10.062) | 0.832 |
SII | ||||
 > 935 | Reference |  | Reference |  |
 ≤ 935 | 0.275(0.104–0.729) | 0.009 | 14.322(0.783–261.811) | 0.073 |
SIS | ||||
 0 | Reference |  |  |  |
 1 | 0.555(0.156–1.978) | 0.364 |  |  |
 2 | 1.667(0.515–5.393) | 0.393 |  |  |