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  1. Up till now, there are still controversies about the specific indication of endoscopic resection for small gastric subepithelial tumors (gSETs) originating from muscularis propria. We aimed to investigate the ...

    Authors: Jinlong Hu, Xinzhu Sun, Nan Ge, Sheng Wang, Jintao Guo, Xiang Liu, Guoxin Wang and Siyu Sun
    Citation: BMC Gastroenterology 2022 22:182
  2. Neuromuscular choristoma (NMC) is a rare peripheral nerve lesion that is composed of ectopic mature muscle fibers and nerve fascicles, typically involving major nerve roots or trunks, such as the cranial nerve...

    Authors: Wei Zhao and Xinying Zhu
    Citation: BMC Gastroenterology 2022 22:180
  3. The aims of the present study are to evaluate non-invasive screening tests for autoimmune gastritis (AIG) and re-evaluate histopathological classification.

    Authors: Yasuhiro Wada, Shigemi Nakajima, Naoko Mori, Shizuki Takemura, Rena Chatani, Mariko Ohara, Makoto Fujii, Hiroshi Hasegawa, Kiyoyuki Hayafuji, Ryoji Kushima and Kazunari Murakami
    Citation: BMC Gastroenterology 2022 22:179
  4. Gastrointestinal malignant melanoma is a rare mucosal melanoma (MM). Other MM include the respiratory and the genitourinary tract. All mucosal melanomas have a poor prognosis when compared to cutaneous melanom...

    Authors: Niraj James Shah, Mark M. Aloysius, Eldrin Bhanat, Shweta Gupta, Ganesh Aswath, Savio John, Shou-Jiang Tang and Hemant Goyal
    Citation: BMC Gastroenterology 2022 22:178
  5. Tofacitinib is an oral, small molecule JAK inhibitor for the treatment of UC. We aimed to describe the real-world treatment experience and corticosteroid utilisation of patients treated with tofacitinib in a U...

    Authors: Michael V. Chiorean, Jessica R. Allegretti, Puza P. Sharma, Benjamin Chastek, Leonardo Salese, Elizabeth J. Bell, Jesse Peterson-Brandt, Joseph C. Cappelleri, Xiang Guo and Nabeel Khan
    Citation: BMC Gastroenterology 2022 22:177

    The Correction to this article has been published in BMC Gastroenterology 2022 22:356

  6. The presence of inflammation is a key hallmark of cancer and, plays an important role in disease progression and survival in colorectal cancer (CRC). Calprotectin detected in the faeces is a sensitive measure ...

    Authors: Fiona A. Ross, James H. Park, David Mansouri, Emilie Combet, Paul G. Horgan, Donald C. McMillan and Campbell S. D. Roxburgh
    Citation: BMC Gastroenterology 2022 22:176
  7. This study was to observe the diagnostic efficacy of high resolution total colonic intracavitary manometry (HRCM) vs colonic transit test (CTT) in the assessment of functional constipation (FC) in Chinese pati...

    Authors: Dan Wang, Zhao Zhang, Mingsen Li, Tingting Liu, Chao Chen, Jiying Cong, Chenmeng Jiao and Yuwei Li
    Citation: BMC Gastroenterology 2022 22:175
  8. Gastric glomus tumor (GGT) is a rare neoplasm that is difficult to distinguish from other gastric submucosal tumors due to a lack of diagnostic experience. The goal of this study was to better understand GGT b...

    Authors: Jing-jing Xing, Wen-peng Huang, Fang Wang, Ya-ru Chai and Jian-bo Gao
    Citation: BMC Gastroenterology 2022 22:174
  9. Primary signet ring cell carcinoma of the colon and rectum (PSRCCR) is rare, usually diagnosed at advanced stage with poor outcomes. We aimed to find possible diagnostic clues in order to help diagnosis.

    Authors: Meng-Tzu Weng, Ko-Han Chao, Chien-Chih Tung, Hao-Chun Chang, I-Lun Shih, Been-Ren Lin, Ming-Jium Shieh, Chia-Tung Shun, Jau-Min Wong and Shu-Chen Wei
    Citation: BMC Gastroenterology 2022 22:173
  10. Environmental enteric dysfunction is a subclinical intestinal disorder characterized by gut inflammation accompanied by morphological changes, such as blunted villi and crypt hyperplasia. This is a common illn...

    Authors: Zemichael Gizaw, Alemayehu Worku Yalew, Bikes Destaw Bitew, Jiyoung Lee and Michael Bisesi
    Citation: BMC Gastroenterology 2022 22:172
  11. Since 2003, a progressive increase in sexually transmitted infections (STI), presented as proctitis, has been described in homosexual men. In 2013 Arnold et al. described microscopic features that enable patho...

    Authors: Fernando Arévalo, Soledad Rayme, Fiorella Zurita, Rocio Ramírez, David Franco, Pedro Montes, Jaime Fustamante and Eduardo Monge
    Citation: BMC Gastroenterology 2022 22:171
  12. Acute lower gastrointestinal bleeding (LGIB) is a common cause of emergency hospitalization and may require readmission for re-bleeding. Recently, a novel endoscopic hemostatic powder (UI-EWD/Nexpowder™, Nextb...

    Authors: Boram Cha, Donghyun Lee, Jongbeom Shin, Jin-Seok Park, Gye-suk Kwon and Hyungkil Kim
    Citation: BMC Gastroenterology 2022 22:170
  13. Glucocorticoids contribute to the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Natural killer T cells play a role in the pathogenesis of NAFLD and response to steroids. The present study aimed to...

    Authors: Tomer Adar, Ami Ben Ya’acov, Yehudit Shabat, Meir Mizrahi, Lida Zolotarov, Yoav Lichtenstein and Yaron Ilan
    Citation: BMC Gastroenterology 2022 22:169
  14. Various conditions with cellular decay are associated with elevated cell-free DNA (cfDNA). This study aimed to investigate if perioperatively measured cfDNA levels were associated with the surgical approach, c...

    Authors: Andreas W. Rosen, Mikail Gögenur, Isabella W. Paulsen, Jesper Olsen, Susanne Eiholm, Lene T. Kirkeby, Ole B. Pedersen, Niels Pallisgaard and Ismail Gögenur
    Citation: BMC Gastroenterology 2022 22:168
  15. While role of ALDOB-related gene variants for hereditary fructose intolerance is well established, contribution of gene variants for acquired fructose malabsorption (e.g. SLC2A5, GLUT5) is not well understood.

    Authors: Irina Taneva, Dorothee Grumann, Dietmar Schmidt, Elina Taneva, Ulrike von Arnim, Thomas Ansorge and Thomas Wex
    Citation: BMC Gastroenterology 2022 22:167
  16. Anorectal malignant melanoma (ARMM) and low rectal adenocarcinoma (LRAC) have some similarities in clinical behaviors, histopathological characteristics and ultrasonographic findings, diagnostic errors are com...

    Authors: Jingwen Yan, Jigang Jing, Shuang Wu, Lacong Geiru and Hua Zhuang
    Citation: BMC Gastroenterology 2022 22:165
  17. Dyspepsia is a common complaint in upper gastrointestinal disorders. It is described as predominant epigastric pain lasting for at least one month. Globally, peptic ulcer disease occurs in 3.5–32% of patients ...

    Authors: Belete Assefa, Abilo Tadesse, Zenahebezu Abay, Alula Abebe, Tsebaot Tesfaye, Melaku Tadesse and Ayenew Molla
    Citation: BMC Gastroenterology 2022 22:164
  18. Estimates of cervical lymph node (LN) metastasis in patients with middle and lower thoracic esophageal squamous cell carcinoma (ESCC) are important. A nomogram is a useful tool for individualized prediction.

    Authors: Zhaoyang Yan, Xinjian Xu, Juntao Lu, Yang You, Jinsheng Xu and Tongxin Xu
    Citation: BMC Gastroenterology 2022 22:163
  19. The long-term prognosis of patients with hepatitis B virus–related acute-on-chronic liver failure (HBV-ACLF) is not well characterised. We assessed long-term outcomes and the associated risk factors of HBV-ACL...

    Authors: Lu Wang, Wenxiong Xu, Xuejun Li, Dabiao Chen, Yeqiong Zhang, Yuanli Chen, Juan Wang, Qiumin Luo, Chan Xie and Liang Peng
    Citation: BMC Gastroenterology 2022 22:162
  20. Non-traumatic hemoperitoneum was a rare event with the risk of sudden death. Spontaneous rupture of hepatocellular carcinoma is the most intuitive diagnosis when hemoperitoneum occurs in cirrhotic patients who...

    Authors: W. S. Yu, M. H. Chang, H. L. Lee, Y. T. Lee, M. C. Tsai and C. C. Wang
    Citation: BMC Gastroenterology 2022 22:160
  21. Sarcopenia is associated with disability, mortality, and poorer survival in cirrhotic patients. For the evaluation of muscle volume, computed tomography (CT) is the most accurate tool. Unfortunately, it would ...

    Authors: Lalida Luengpradidgun, Naichaya Chamroonkul, Pimsiri Sripongpun, Apichat Kaewdech, Pramot Tanutit, Natee Ina and Teerha Piratvisuth
    Citation: BMC Gastroenterology 2022 22:159
  22. The prevalence of non-alcoholic fatty liver disease (NAFLD) is rising at an exponential rate throughout the world. Given the confirmed association between nutritional status and NAFLD, this study aimed to inve...

    Authors: Nasir Talenezhad, Farhang Mirzavandi, Shahab Rahimpour, Amir Pasha Amel Shahbaz, Mohammad Mohammadi and Mahdieh Hosseinzadeh
    Citation: BMC Gastroenterology 2022 22:158
  23. Primary malignant melanoma of esophagus (PMME) is an extremely rare disease with poor prognosis. We aimed to determine the clinical characteristics and treatment outcomes of patients with PMME.

    Authors: Tae-Se Kim, Byung-Hoon Min, Yang Won Min, Hyuk Lee, Poong-Lyul Rhee, Jae J. Kim and Jun Haeng Lee
    Citation: BMC Gastroenterology 2022 22:157
  24. In this study, we aimed to identify the distribution of presenting laboratory and nonenhanced computed tomography (CT) imaging features within 48 h before percutaneous cholecystostomy (PC) and create a model t...

    Authors: Bai-Qing Chen, Feng Xie, Guo-Dong Chen, Xue Li, Xue Mao and Bao Jia
    Citation: BMC Gastroenterology 2022 22:155
  25. Various hemostatic devices have been utilized to reduce blood loss during hepatectomy. Nonetheless, a comparison between monopolar and bipolar coagulation, particularly their usefulness or inferiority, has bee...

    Authors: Ryuta Muraki, Yoshifumi Morita, Shinya Ida, Ryo Kitajima, Satoru Furuhashi, Makoto Takeda, Hirotoshi Kikuchi, Yoshihiro Hiramatsu, Atsuko Fukazawa, Takanori Sakaguchi, Mayu Fukushima, Eisaku Okada and Hiroya Takeuchi
    Citation: BMC Gastroenterology 2022 22:154
  26. Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest gastrointestinal cancers with a 5-year survival rate of less than 10%. Biomarkers for early PDAC detection are useful in treating patients with P...

    Authors: Haruki Odaka, Keiko Hiemori, Asako Shimoda, Kazunari Akiyoshi and Hiroaki Tateno
    Citation: BMC Gastroenterology 2022 22:153
  27. Gallbladder cancer (GBC) with liver metastasis is considered unresectable. However, there have been infrequent reports of long-term survival in patients with GBC and liver metastases. Therefore, we examined th...

    Authors: Ryota Higuchi, Hiroaki Ono, Ryusei Matsuyama, Yusuke Takemura, Shinjiro Kobayashi, Takehito Otsubo, Yuta Abe, Itaru Endo, Minoru Tanabe and Masakazu Yamamoto
    Citation: BMC Gastroenterology 2022 22:152
  28. Selective internal radiation therapy (SIRT) with yttrium-90 (90Y) resin microspheres is an established locoregional treatment option for unresectable hepatocellular carcinoma (HCC), which delivers a lethal dose o...

    Authors: Armeen Mahvash, Steven Chartier, Mark Turco, Paula Habib, Steven Griffith, Scott Brown and S. Cheenu Kappadath
    Citation: BMC Gastroenterology 2022 22:151
  29. Pneumatosis cystoides intestinalis (PCI) is a rare condition characterized by the presence of air collection within the subserosa and/or submucosa of the gastrointestinal wall. Due to the lack of specific symp...

    Authors: Liqing Yang, Xi Zhong, Hao Yang, Qin Wu, Yuping Gong and Bo Wang
    Citation: BMC Gastroenterology 2022 22:150
  30. Behçet’s disease (BD) is a recurrent multisystem inflammatory disease. Anti-tumor necrosis factor (TNF) α agents have been used to treat patients with intestinal BD with severe disease activity or those who ar...

    Authors: Haruka Miyazaki, Daisuke Watanabe, Norihiro Okamoto, Eri Tokunaga, Yuna Ku, Haruka Takenaka, Namiko Hoshi, Makoto Ooi and Yuzo Kodama
    Citation: BMC Gastroenterology 2022 22:149
  31. Many studies have focused on prophylactic therapy for post-endoscopic submucosal dissection (ESD) of esophageal strictures. However, various strategies cannot prevent the occurrence of postoperative strictures...

    Authors: Qing Lu, Jin Wang, Xiuhe Lv, Mingjia Xi, Tiantian Lei, Zijing Wang, Li Yang and Jinlin Yang
    Citation: BMC Gastroenterology 2022 22:147
  32. Analysis of the constituents of gallstones using various spectroscopic techniques assists in identification of the pathogenesis of gallstones. In the current study, using Fourier Transform Infra-Red (FTIR) Spe...

    Authors: Lena Jafri, Muhammad Abbas Abid, Humera Asif, Bilal Hashmi, Hafsa Majid, Farooq Ghani, Sibtain Ahmed, Imran Siddiqui and Aysha Habib Khan
    Citation: BMC Gastroenterology 2022 22:146
  33. Ornithine transcarbamylase deficiency (OTCD) is most common among urea cycle disorders (UCDs), defined by defects in enzymes associated with ureagenesis. Corticosteroid administration to UCD patients, includin...

    Authors: Koji Imoto, Masatake Tanaka, Takeshi Goya, Tomomi Aoyagi, Motoi Takahashi, Miho Kurokawa, Shigeki Tashiro, Masaki Kato, Motoyuki Kohjima and Yoshihiro Ogawa
    Citation: BMC Gastroenterology 2022 22:144
  34. Therapeutic options for inflammatory bowel disease (IBD) have increased since the introduction of tumour necrosis factor (TNF) inhibitors a few decades ago. However, direct comparisons of the effectiveness of ...

    Authors: Hye Kyung Hyun, Hyun-Soo Zhang, Jongwook Yu, Eun Ae Kang, Jihye Park, Soo Jung Park, Jae Jun Park, Tae Il Kim, Won Ho Kim and Jae Hee Cheon
    Citation: BMC Gastroenterology 2022 22:143
  35. The relationship between PROX1 expression and clinicopathological characteristics and prognosis in patients with gastric cancer (GC) remain controversial. The aim of this study is to determine the clinicopatho...

    Authors: Zirui Jia, Yuhang Wang, Jiacheng Gao and Guo Zu
    Citation: BMC Gastroenterology 2022 22:142
  36. Regional lymph node metastases are the main adverse prognostic factor in patients with rectal cancer without distant metastases. There are discrepancies, however, regarding additional risk factors in the group...

    Authors: Marcin Zeman, Władysław Skałba, Piotr Szymański, Grzegorz Hadasik, Dmytro Żaworonkow, Dominik A. Walczak and Agnieszka Czarniecka
    Citation: BMC Gastroenterology 2022 22:141
  37. Hospitalization admissions and discharge databases (DAD) using the International Classification of Diseases (ICD) codes are often used to describe the epidemiology of Clostridioides difficile infections (CDI) amo...

    Authors: Seth R. Shaffer, Zoann Nugent, Charles N. Bernstein, Andrew Walkty and Harminder Singh
    Citation: BMC Gastroenterology 2022 22:140
  38. It is unclear whether prophylactic endoscopic closure after colorectal endoscopic submucosal dissection (ESD) reduces the risk of postoperative adverse events due to variability in lesion characteristics. Ther...

    Authors: Jun Omori, Osamu Goto, Tsugumi Habu, Yumiko Ishikawa, Kumiko Kirita, Eriko Koizumi, Hiroto Noda, Kazutoshi Higuchi, Takeshi Onda, Teppei Akimoto, Naohiko Akimoto, Norio Itokawa, Mitsuru Kaise and Katsuhiko Iwakiri
    Citation: BMC Gastroenterology 2022 22:139

    The Correction to this article has been published in BMC Gastroenterology 2022 22:206

  39. Ulcerative colitis (UC) is a common inflammatory bowel disease, during which cell necroptosis plays key roles in driving inflammation initiation and aggravation. Previous studies reported Receptor Interacting ...

    Authors: Chaoqin Duan, Xi Xu, Xiaoyi Lu, Ling Wang and Zhongkai Lu
    Citation: BMC Gastroenterology 2022 22:137
  40. Pancreatic portal hypertension (PPH) is a type of extrahepatic portal hypertension. We compared the clinical efficacy of different treatment methods for PPH caused by splenic vein stenosis in chronic pancreati...

    Authors: Jingjing Liu, Qingbing Wang, Xiaoyi Ding, Qin Liu, Wei Huang, Junwei Gu, Zhongmin Wang, Wei Wu and Zhiyuan Wu
    Citation: BMC Gastroenterology 2022 22:136
  41. In a randomized controlled trial, lenvatinib was non-inferior to sorafenib in overall survival (OS) of patients with unresectable hepatocellular carcinoma (uHCC). This study aimed to compare the effects of sor...

    Authors: Na Ryung Choi, Ju Yeon Kim, Ji Hoon Hong, Moon Haeng Hur, Heejin Cho, Min Kyung Park, Jihye Kim, Yun Bin Lee, Eun Ju Cho, Jeong-Hoon Lee, Su Jong Yu, Jung-Hwan Yoon and Yoon Jun Kim
    Citation: BMC Gastroenterology 2022 22:135
  42. Remnant cholesterol/high-density lipoprotein cholesterol (RC/HDL-C) ratio has been shown to be a good predictor of metabolic disease risk, but no studies have further investigated the role of RC/HDL-C ratio in...

    Authors: Yang Zou, Chong Hu, Maobin Kuang and Yuliang Chai
    Citation: BMC Gastroenterology 2022 22:134
  43. Patients can present for a wide variety of etiologies for dysphagia, and it is important to consider less common causes once common etiologies have been ruled out. Extrapulmonary Mycobacterium tuberculosis (TB) p...

    Authors: Dylan Olson, Kevin C. Liu, Anthony P. Merza, Ermias Tilahun and A. Aziz Aadam
    Citation: BMC Gastroenterology 2022 22:131

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