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  1. There is a strong rationale for the use of agents with film-forming protective properties, like xyloglucan, for the treatment of acute diarrhea. However, few data from clinical trials are available.

    Authors: Lucio Gnessi, Vladimir Bacarea, Marius Marusteri and Núria Piqué
    Citation: BMC Gastroenterology 2015 15:153
  2. The purpose of this study was to investigate the effects of sub-chronic high fat, high sucrose diet (also termed ‘Westernized diet’ or WD) feeding on the liver transcriptome during early nonalcoholic fatty liv...

    Authors: Michael D. Roberts, C. Brooks Mobley, Ryan G. Toedebush, Alexander J. Heese, Conan Zhu, Anna E. Krieger, Clayton L. Cruthirds, Christopher M. Lockwood, John C. Hofheins, Charles E. Wiedmeyer, Heather J. Leidy, Frank W. Booth and R. Scott Rector
    Citation: BMC Gastroenterology 2015 15:151
  3. In cases of difficult bile duct cannulation, the use of wire-guided cannulation over a pancreatic stent (WGC-PS) or the double guidewire technique (DGT) may facilitate biliary cannulation. The aim of this stud...

    Authors: Min Jae Yang, Jae Chul Hwang, Byung Moo Yoo, Jin Hong Kim, Hyoung-Kyu Ryu, Soon Sun Kim, Joon Koo Kang and Min Kyeong Kim
    Citation: BMC Gastroenterology 2015 15:150
  4. Pyoderma Gangrenosum (PG) is a cutaneous condition, its diagnosis suggested by the presence of a painful cutaneous ulcer showing rapid progression. Pyoderma gangrenosum is associated with a concomitant systemi...

    Authors: Theodoros Androutsakos, Paraskevas Stamopoulos, Kiriaki Aroni and Gregorios Hatzis
    Citation: BMC Gastroenterology 2015 15:149
  5. Histone deacetylases (HDACs) have been associated with malignant tumor development and progression in humans. HDAC inhibitors (HDACIs) are currently being explored as anti-cancer agents in clinical trials. The...

    Authors: Constantinos Giaginis, Christos Damaskos, Ioannis Koutsounas, Adamantia Zizi-Serbetzoglou, Nicolaos Tsoukalas, Efstratios Patsouris, Gregorios Kouraklis and Stamatios Theocharis
    Citation: BMC Gastroenterology 2015 15:148
  6. Early occurrence of immunosuppression is a risk factor for infected pancreatic necrosis (IPN) in the patients with acute pancreatitis (AP). However, current measures for the immune systems are too cumbersome a...

    Authors: Xiao Shen, Jing Sun, Lu Ke, Lei Zou, Baiqiang Li, Zhihui Tong, Weiqin Li, Ning Li and Jieshou Li
    Citation: BMC Gastroenterology 2015 15:147
  7. The role of clinical parameters such as systemic inflammatory response syndrome (SIRS) criteria in predicting the infection remains unclear in cirrhosis patients. The aim was to evaluate the usefulness of infl...

    Authors: Jung Hyun Kwon, Jeong Won Jang, Young Woon Kim, Sung Won Lee, Soon Woo Nam, Dongwook Jaegal, Seungok Lee and Si Hyun Bae
    Citation: BMC Gastroenterology 2015 15:146
  8. Distal diminutive colorectal polyps are common and accurate endoscopic prediction of hyperplastic or adenomatous polyp histology could reduce procedural time, costs and potential risks associated with the rese...

    Authors: Timo Rath, Gian E. Tontini, Andreas Nägel, Michael Vieth, Steffen Zopf, Claudia Günther, Arthur Hoffman, Markus F. Neurath and Helmut Neumann
    Citation: BMC Gastroenterology 2015 15:145
  9. The role of HLA-DR antigens in the clinicopathological features of autoimmune hepatitis (AIH) is not clearly understood. We examined the implications of HLA-DR antigens in Japanese AIH, including the effect of...

    Authors: Yohei Furumoto, Toru Asano, Tomonori Sugita, Hiroshi Abe, Yoshimichi Chuganji, Kazuhiko Fujiki, Akihiko Sakata and Yoshio Aizawa
    Citation: BMC Gastroenterology 2015 15:144
  10. Helicobacter pylori infection is the most important risk factor for gastric cancer, for which eradication therapy is commonly performed. However, gastric cancer is sometimes discovered...

    Authors: Kosuke Sakitani, Yoshihiro Hirata, Nobumi Suzuki, Satoki Shichijo, Ayako Yanai, Takako Serizawa, Kei Sakamoto, Masao Akanuma, Shin Maeda, Yutaka Yamaji, Yasuhiko Iwamoto, Shoji Kawazu and Kazuhiko Koike
    Citation: BMC Gastroenterology 2015 15:143
  11. The Tokyo guidelines provide criteria for the diagnosis and classification of acute cholecystitis in three severity grades. However, no data exists on the predictive value of these guidelines. The aim of this ...

    Authors: Peter C. Ambe, Hildegard Christ and Dirk Wassenberg
    Citation: BMC Gastroenterology 2015 15:142
  12. Celiac disease, Crohn disease and ulcerative colitis are inflammatory disorders of the gastrointestinal tract with some common genetic, immunological and environmental factors involved in their pathogenesis. S...

    Authors: Dorottya Kocsis, Zsuzsanna Tóth, Ágnes A. Csontos, Pál Miheller, Péter Pák, László Herszényi, Miklós Tóth, Zsolt Tulassay and Márk Juhász
    Citation: BMC Gastroenterology 2015 15:141
  13. Acute kidney injury (AKI) is known to increase mortality in hospitalized cirrhotic patients; therefore early identification is utmost significance. There are only a few studies evaluating the cut-off level of ...

    Authors: Sombat Treeprasertsuk, Amornpun Wongkarnjana, Veeravich Jaruvongvanich, Sasipim Sallapant, Khajohn Tiranathanagul, Piyawat Komolmit and Pisit Tangkijvanich
    Citation: BMC Gastroenterology 2015 15:140
  14. Trans-anal irrigation (TAI) is used widely to treat bowel dysfunction, although evidence for its use in adult chronic functional constipation remains unclear. Long-term outcome data are lacking, and the effect...

    Authors: Christopher D. Emmett, Helen J. Close, Yan Yiannakou and James M. Mason
    Citation: BMC Gastroenterology 2015 15:139
  15. Several studies have investigated the effect of intraoperative blood loss (IBL) on recurrence of tumors. However, the independent effect of IBL on oncological outcome after liver transplantation (LT) for hepat...

    Authors: Bing Liu, Fei Teng, Hong Fu, Wen-Yuan Guo, Xiao-Min Shi, Zhi-Jia Ni, Xiao-Gang Gao, Jun Ma, Zhi-Ren Fu and Guo-Shan Ding
    Citation: BMC Gastroenterology 2015 15:138
  16. The choice of infant formula is thought to play an important role on gastric emptying (GE) in a variety of gastrointestinal disorders. It is known that many ingredients impact on GE, including the type of prot...

    Authors: Rosan Meyer, Ru-Xin Melanie Foong, Nikhil Thapar, Stamatiki Kritas and Neil Shah
    Citation: BMC Gastroenterology 2015 15:137
  17. To assess hepatobiliary (HB) scans for predicting recurrent symptoms in nonoperated patients with mild or vague symptomatic gallstones.

    Authors: Keun Soo Ahn, Ho-Seong Han, Jai Young Cho, Yoo-Seok Yoon, Chulhan Kim and Won Woo Lee
    Citation: BMC Gastroenterology 2015 15:136
  18. Endoscopic sphincterotomy (ES) is a therapeutic technique developed as an advanced application of endoscopic retrograde cholangiopancreatography (ERCP). An important adverse event associated with this procedur...

    Authors: Feng Liu, Guang-Yong Wang and Zhao-Shen Li
    Citation: BMC Gastroenterology 2015 15:135
  19. Hepatic injury has been reported following duloxetine use. This study further examines the hepatic safety of duloxetine in a large US health insurance database.

    Authors: Nancy D. Lin, Heather Norman, Arie Regev, David G. Perahia, Hu Li, Curtis Liming Chang and David D. Dore
    Citation: BMC Gastroenterology 2015 15:134
  20. Coeliac disease is characterised by villous atrophy, which usually normalises after gluten withdrawal. Sometimes the revaluation of duodenal histology is required during follow-up, even if the methodology for ...

    Authors: Luca Elli, Enea Zini, Carolina Tomba, Maria Teresa Bardella, Silvano Bosari, Dario Conte, Letterio Runza, Leda Roncoroni and Stefano Ferrero
    Citation: BMC Gastroenterology 2015 15:133
  21. Both double-balloon enteroscopy (DBE) and video capsule endoscopy (VCE) have similar diagnostic yields for patients with overt obscure gastrointestinal bleeding (OGIB). However, the choice of initial modality ...

    Authors: Yoshimasa Maeda, Kosaku Moribata, Hisanobu Deguchi, Izumi Inoue, Takao Maekita, Mikitaka Iguchi, Hideyuki Tamai, Jun Kato and Masao Ichinose
    Citation: BMC Gastroenterology 2015 15:132
  22. Recent studies have demonstrated an association between short-term elevations in air pollution and an increased risk of exacerbating gastrointestinal disease. The objective of the study was to evaluate if day-...

    Authors: Samuel Quan, Hong Yang, Divine Tanyingoh, Paul J. Villeneuve, David M. Stieb, Markey Johnson, Robert Hilsden, Karen Madsen, Sander Veldhuyzen van Zanten, Kerri Novak, Eddy Lang, Subrata Ghosh and Gilaad G. Kaplan
    Citation: BMC Gastroenterology 2015 15:131
  23. Constipation is a frequently reported bowel symptom in the elderly with considerable impact on quality of life and health expenses. Disease-related morbidity and even mortality have been reported in the affect...

    Authors: Roberto De Giorgio, Eugenio Ruggeri, Vincenzo Stanghellini, Leonardo H. Eusebi, Franco Bazzoli and Giuseppe Chiarioni
    Citation: BMC Gastroenterology 2015 15:130
  24. Early manifestations of pediatric inflammatory bowel disease (IBD) can be relatively nonspecific. Initial mucosal biopsies may not be conclusive, delaying the diagnosis until subsequent biopsies demonstrate ty...

    Authors: Julie A. Bass, Craig A. Friesen, Amanda D. Deacy, Nancy A. Neilan, Julia M. Bracken, Valentina Shakhnovich and Vivekanand Singh
    Citation: BMC Gastroenterology 2015 15:129
  25. Mucosal Schwann-cell hamartoma is a rare mesenchymal polyp that presents in the intestine. Despite lacking ganglion cells, it resembles a gastrointestinal ganglioneuroma.

    Authors: Jeong Mo Bae, Joon Young Lee, Junhun Cho, Sang Ah Lim and Gyeong Hoon Kang
    Citation: BMC Gastroenterology 2015 15:128
  26. There a shortage of robust information about profiles of gastrointestinal disease in sub-Saharan Africa. The endoscopy unit of the University Teaching Hospital in Lusaka has been running without interruption s...

    Authors: Violet Kayamba, Edford Sinkala, Stayner Mwanamakondo, Rose Soko, Boniface Kawimbe, Beatrice Amadi, Isaac Zulu, Jean-Baptiste Nzaisenga, Themba Banda, Chipasha Mumbwe, Evans Phiri, Philip Munkonge and Paul Kelly
    Citation: BMC Gastroenterology 2015 15:127
  27. Pyogenic granuloma (PG) is a polypoid lobular capillary hemangioma rarely observed in the gastrointestinal tract. Only a few cases in the small bowel have been described in the literature.

    Authors: Shun-ichi Misawa, Hiroto Sakamoto, Akira Kurogochi, Yasushi Kirii, Shinichiro Nakamura, Tomoko Misawa, Suguru Yoneda, Mari Hirano, Osamu Owa, Hiroyuki Takagi and Hiroyoshi Ota
    Citation: BMC Gastroenterology 2015 15:126
  28. Impaired growth is a well-known complication in celiac disease, but factors associated with it are poorly known. We investigated this issue in a large cohort of children.

    Authors: Samuli Nurminen, Laura Kivelä, Juha Taavela, Heini Huhtala, Markku Mäki, Katri Kaukinen and Kalle Kurppa
    Citation: BMC Gastroenterology 2015 15:125
  29. In this era of a constantly changing landscape of antiviral treatment options for chronic viral hepatitis C (CHC), shared clinical decision-making addresses the need to engage patients in complex treatment dec...

    Authors: Jessica L. Zuchowski, Alison B. Hamilton, Jeffrey M. Pyne, Jack A. Clark, Aanand D. Naik, Donna L. Smith and Fasiha Kanwal
    Citation: BMC Gastroenterology 2015 15:124
  30. Demand for endoscopic procedures scheduled with anesthesia is increasing and no-show to appointments carries significant patient health and financial impact, yet little is known about predictors of no-show.

    Authors: Jennifer T. Chang, Justin L. Sewell and Lukejohn W. Day
    Citation: BMC Gastroenterology 2015 15:123
  31. Biopsy needles have recently been developed to obtain both cytological and histological specimens during endoscopic ultrasound (EUS). We conducted this study to compare 22-gauge (G) fine needle aspiration (FNA...

    Authors: Min Jae Yang, Hyunee Yim, Jae Chul Hwang, Dakeun Lee, Young Bae Kim, Sun Gyo Lim, Soon Sun Kim, Joon Koo Kang, Byung Moo Yoo and Jin Hong Kim
    Citation: BMC Gastroenterology 2015 15:122
  32. Esophagogastroduodenal pneumatosis is the presence of air in esophagus, stomach, and duodenum simultaneously, which have never been described in the literature. Intramural duodenal hematoma (IDH) rarely occurs...

    Authors: Wei-Cheng Huang, Chih-Hsin Lee and Fat-Moon Suk
    Citation: BMC Gastroenterology 2015 15:121
  33. The most common malignancy to cause gastric outlet obstruction is primary gastric adenocarcinoma and it is followed by carcinoma of the pancreas and gallbladder. Herein, we report a case of gastric outlet obst...

    Authors: Alexander H. Kim, M. Joshua Shellenberger, Zong Ming Chen and Jinhong Li
    Citation: BMC Gastroenterology 2015 15:120
  34. Metabolic alterations relevant to postprandial dyslipidemia were previously identified in the intestine of obese insulin-resistant subjects. The aim of the study was to identify the genes deregulated by system...

    Authors: Alain Veilleux, Sylvain Mayeur, Jean-Christophe Bérubé, Jean-François Beaulieu, Eric Tremblay, Frédéric-Simon Hould, Yohan Bossé, Denis Richard and Emile Levy
    Citation: BMC Gastroenterology 2015 15:119
  35. Everolimus (EVE), a mammalian target of rapamycin inhibitor, has been proposed as liver transplant immunosuppressive drug, gaining wide interest also for the treatment of cancer. Although an appropriate tolera...

    Authors: Valentina Masola, Amedeo Carraro, Gianluigi Zaza, Gloria Bellin, Umberto Montin, Paola Violi, Antonio Lupo and Umberto Tedeschi
    Citation: BMC Gastroenterology 2015 15:118
  36. The prevalence of gastroesophageal reflux disease (GERD) has been increasing worldwide, with proton pump inhibitor (PPI) administration the current mainstay therapy for affected individuals. However, PPI effic...

    Authors: Norihisa Ishimura, Mami Mori, Hironobu Mikami, Shino Shimura, Goichi Uno, Masahito Aimi, Naoki Oshima, Shunji Ishihara and Yoshikazu Kinoshita
    Citation: BMC Gastroenterology 2015 15:117
  37. Epidemiologic studies of alcoholic hepatitis (AH) have been hindered by the lack of a validated International Classification of Disease (ICD) coding algorithm for use with administrative data. Our objective wa...

    Authors: Jack XQ Pang, Erin Ross, Meredith A. Borman, Scott Zimmer, Gilaad G. Kaplan, Steven J. Heitman, Mark G. Swain, Kelly W. Burak, Hude Quan and Robert P. Myers
    Citation: BMC Gastroenterology 2015 15:116
  38. The plasticity region of Helicobacter pylori (H. pylori) is a large chromosomal segment containing strain-specific genes. The prevalence of the plasticity region genes of the H. pylori strains in China remains un...

    Authors: Yanan Gong, Xianhui Peng, Lihua He, Hao Liang, Yuanhai You and Jianzhong Zhang
    Citation: BMC Gastroenterology 2015 15:115
  39. Emphysematous cholecystitis is a severe variant of acute cholecystitis caused by anaerobic bacteria. Although intraperitoneal air as a complication has been described in association with emphysematous cholecys...

    Authors: Yasumichi Yagi, Shozo Sasaki, Itsuro Terada, Akemi Yoshikawa, Wataru Fukushima, Hirohisa Kitagawa, Takashi Fujimura, Ryohei Izumi and Katsuhiko Saito
    Citation: BMC Gastroenterology 2015 15:114
  40. Hepatocellular Carcinoma (HCC) is a common malignancy occurring globally but with a dismal prognosis. Des-gamma-carboxyprothrombin (DCP) has been reported to be more sensitive and specific than Alpha-fetoprote...

    Authors: Akpakip I. Ette, Dennis A. Ndububa, Olusegun Adekanle and Udeme Ekrikpo
    Citation: BMC Gastroenterology 2015 15:113
  41. Recent works provide evidence of the importance of the prostaglandin D2 (PGD2) metabolic pathway in inflammatory bowel diseases. We investigated the expression of PGD2 metabolic pathway actors in Crohn’s disea...

    Authors: Anne-Gaelle Le Loupp, Kalyane Bach-Ngohou, Arnaud Bourreille, Hélène Boudin, Malvyne Rolli-Derkinderen, Marc G. Denis, Michel Neunlist and Damien Masson
    Citation: BMC Gastroenterology 2015 15:112
  42. Postprandial accumulation of gastric secretions in the proximal stomach above the meal adjacent to the esophagogastric junction (EGJ), referred to as the ‘acid pocket’, has been proposed as a pathophysiologica...

    Authors: Andreas Steingoetter, Matthias Sauter, Jelena Curcic, Dian Liu, Dieter Menne, Michael Fried, Mark Fox and Werner Schwizer
    Citation: BMC Gastroenterology 2015 15:111
  43. It is important to devise efficient and easy methods of detecting colorectal tumours to reduce mortality from colorectal cancer. Dual-wavelength excitation autofluorescence intensity can be used to visualize c...

    Authors: Yoko Kominami, Shigeto Yoshida, Shinji Tanaka, Rie Miyaki, Yoji Sanomura, Min-Woong Seo, Keiichiro Kagawa, Shoji Kawahito, Hidenobu Arimoto, Kenji Yamada and Kazuaki Chayama
    Citation: BMC Gastroenterology 2015 15:110
  44. Pancreatic ductal adenocarcinoma (PDAC) is characterized by an extensive desmoplastic stromal response. Fibroblast activation protein-α (FAP) is best known for its presence in stromal cancer-associated fibrobl...

    Authors: Tomoya Kawase, Yumiko Yasui, Sohji Nishina, Yuichi Hara, Izumi Yanatori, Yasuyuki Tomiyama, Yoshihiro Nakashima, Koji Yoshida, Fumio Kishi, Masafumi Nakamura and Keisuke Hino
    Citation: BMC Gastroenterology 2015 15:109
  45. Small-bowel angioectasias are frequently diagnosed with capsule endoscopy (CE) or balloon endoscopy however, major predictors have not been defined and the indications for endoscopic treatment have not been st...

    Authors: Atsushi Igawa, Shiro Oka, Shinji Tanaka, Sayoko Kunihara, Makoto Nakano, Taiki Aoyama and Kazuaki Chayama
    Citation: BMC Gastroenterology 2015 15:108
  46. Gastric and colorectal cancers have a major impact on public health, and are the most common malignant tumors in China. The aim of this research was to study whether polymorphisms of CHCHD3P1-HSP90AB7P, GRID1, HS...

    Authors: Qinghua Su, Yuan Wang, Jun Zhao, Cangjian Ma, Tao Wu, Tianbo Jin and Jinkai Xu
    Citation: BMC Gastroenterology 2015 15:107
  47. Whitish intraluminal esophageal masses might represent the endoscopic feature of a bezoar or a pedunculated tumor, most likely a fibrovascular polyp, without exclusion of other mesenchymal tumors (leiomyoma, l...

    Authors: Lidia Ciobanu, Oliviu Pascu, Marcel Tantau, Oana Pinzariu, Bogdan Furnea, Emil Botan and Marian Taulescu
    Citation: BMC Gastroenterology 2015 15:106
  48. Biliary leaks have been treated with endoscopic management using different techniques with conflicting results. Furthermore the appropriate rescue therapy for refractory leaks has not been established. We eval...

    Authors: Jorge Canena, David Horta, João Coimbra, Liliane Meireles, Pedro Russo, Inês Marques, Leonel Ricardo, Catarina Rodrigues, Tiago Capela, Diana Carvalho, Rafaela Loureiro, António Mateus Dias, Gonçalo Ramos, António Pereira Coutinho, Carlos Romão and Pedro Mota Veiga
    Citation: BMC Gastroenterology 2015 15:105
  49. Poor response to anti-tumour necrosis factor biologicals like infliximab (IFX) is observed in patients with ulcerative colitis (UC), which may lead to prolonged morbidity and waste of medical resources. We aim...

    Authors: Ryota Iwasa, Akihiro Yamada, Koji Sono, Ryuichi Furukawa, Ken Takeuchi and Yasuo Suzuki
    Citation: BMC Gastroenterology 2015 15:103

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