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  1. To compare the effects of laparoscopic-assisted gastrectomy (LAG) and open gastrectomy (OG) on serum interleukin-6 (IL-6) levels in gastric cancer (GC) patients from Asia.

    Authors: Zhen-Bo Shu, Hai-Ping Cao, Yong-Chao Li and Li-Bo Sun
    Citation: BMC Gastroenterology 2015 15:52
  2. Hereditary transthyretin amyloid (ATTR) amyloidosis is a rare but fatal autosomal dominant condition that is present all over the world. A liver transplantation has been shown to halt the progress of the disea...

    Authors: Jonas Wixner, Torbjörn Sundström, Pontus Karling, Intissar Anan and Ole B Suhr
    Citation: BMC Gastroenterology 2015 15:51
  3. Biologic activities of functional mediators activate downstream transducers regulating inflammation and carcinogenesis. Correlation among mediators (IL-6, IL-27, TNF-α, and VEGF) with STAT proteins at diverse ...

    Authors: Jung-Ta Kao, Chun-Lung Feng, Cheng-Ju Yu, Shu-Mei Tsai, Ping-Ning Hsu, Yao-Li Chen and Yi-Ying Wu
    Citation: BMC Gastroenterology 2015 15:50
  4. Nicotinamide phosphoribosyl transferase (Nampt) plays a crucial role in tumorigenesis. The present study examines whether genetic polymorphisms of NAMPT are related to the risk of developing esophageal squamous c...

    Authors: Chuanzhen Zhang, Daojie Yan, Shanshan Wang, Changqing Xu, Wenjun Du, Tao Ning, Changhong Liu, Meijuan Zhang, Ruiping Hou and Ziping Chen
    Citation: BMC Gastroenterology 2015 15:49
  5. Several systematic reviews (SRs) of randomised controlled trials (RCTs) comparing laparoscopic versus open appendectomy have been published, but there has been no overview of SRs of these two interventions. Th...

    Authors: Thomas Jaschinski, Christoph Mosch, Michaela Eikermann and Edmund AM Neugebauer
    Citation: BMC Gastroenterology 2015 15:48
  6. In the chronically inflamed rabbit small intestine, brush border membrane (BBM) Na-glutamine co-transport is inhibited in villus cells (mediated by B0AT1), while it is stimulated in crypt cells (mediated by SN...

    Authors: Soudamani Singh, Subha Arthur, Jamilur Talukder, Balasubramanian Palaniappan, Steven Coon and Uma Sundaram
    Citation: BMC Gastroenterology 2015 15:47
  7. Many factors have been found to affect the difficulty of colonoscope insertion, such as age, gender, body mass index (BMI), history of abdominal surgery and operator etc. However, a scoring system may be more ...

    Authors: Hui Jia, Limei Wang, Hui Luo, Shaowei Yao, Xiangping Wang, Linhui Zhang, Rui Huang, Zhiguo Liu, Xiaoyu Kang, Yanglin Pan and Xuegang Guo
    Citation: BMC Gastroenterology 2015 15:46
  8. Inflammatory bowel disease (IBD)-like conditions in glycogen storage disease (GSD) type Ib have been predominantly described in children. Signs and symptoms of GSD type Ib are hypoglycemia, pancytopenia and he...

    Authors: Magdalena Sarah Volz, Mani Nassir, Christoph Treese, Moritz von Winterfeld, Ursula Plöckinger, Hans-Jörg Epple and Britta Siegmund
    Citation: BMC Gastroenterology 2015 15:45
  9. Surgical resection is the only curative treatment for pancreatic and periampullary cancer, but many patients undergo unnecessary laparotomy because tumours can be understaged by computerised tomography (CT). A...

    Authors: Stephen Morris, Kurinchi S Gurusamy, Jessica Sheringham and Brian R Davidson
    Citation: BMC Gastroenterology 2015 15:44
  10. Although many of the factors and molecules closely associated with non-alcoholic steatohepatitis (NASH) have been reported, the role of inducible nitric oxide synthase (iNOS)-derived nitric oxide (NO) on the p...

    Authors: Yuichi Nozaki, Koji Fujita, Koichiro Wada, Masato Yoneda, Takaomi Kessoku, Yoshiyasu Shinohara, Kento Imajo, Yuji Ogawa, Makoto Nakamuta, Satoru Saito, Naohiko Masaki, Yoji Nagashima, Yasuo Terauchi and Atsushi Nakajima
    Citation: BMC Gastroenterology 2015 15:42
  11. Patients with gastrointestinal food allergy are characterised by increased production of mast cell derived mediators upon allergen contact and present often with unspecific symptoms. The aim of this study was ...

    Authors: Martin Raithel, Alexander Hagel, Heinz Albrecht, Yurdaguel Zopf, Andreas Naegel, Hanns-Wolf Baenkler, Fred Buchwald, Hans-Wolfgang Schultis, Juergen Kressel, Eckhart Georg Hahn and Peter Konturek
    Citation: BMC Gastroenterology 2015 15:41
  12. Recurrent hepatitis C virus infection after liver transplantation is associated with reduced graft and patient survival. Re-transplantation for graft failure due to recurrent hepatitis C is controversial and n...

    Authors: Julien Vionnet, Manuel Pascual, Haithem Chtioui, Emiliano Giostra, Pietro E Majno, Laurent A Decosterd and Darius Moradpour
    Citation: BMC Gastroenterology 2015 15:38
  13. The aim of the present retrospective study was to analyze clinical outcome and risk factors associated with treatment outcomes according to KRAS status in patient with metastatic colorectal cancer (mCRC) treat...

    Authors: Beatrix Bencsikova, Zbynek Bortlicek, Jana Halamkova, Lenka Ostrizkova, Igor Kiss, Bohuslav Melichar, Tomas Pavlik, Ladislav Dusek, Dalibor Valik, Rostislav Vyzula and Lenka Zdrazilova-Dubska
    Citation: BMC Gastroenterology 2015 15:37
  14. Ischemic pancreatitis is a rare medical entity. The pancreatic tissue is susceptible to ischemia with the possibility of developing acute pancreatitis. The abdominal aortic aneurysm can be one possible cause o...

    Authors: Ileana Cocota, Radu Badea, Traian Scridon and Dan L Dumitrascu
    Citation: BMC Gastroenterology 2015 15:35
  15. Colorectal liver metastases (CLM) occur frequently and postoperative intestinal infection is a common complication. Our previous study showed that probiotics could decrease the rate of infectious complications...

    Authors: Zhihua Liu, Chao Li, Meijin Huang, Chao Tong, Xingwei Zhang, Lei Wang, Hui Peng, Ping Lan, Peng Zhang, Nanqi Huang, Junsheng Peng, Xiaojian Wu, Yanxing Luo, Huanlong Qin, Liang Kang and Jianping Wang
    Citation: BMC Gastroenterology 2015 15:34
  16. Percutaneous liver biopsy (PLB) is the “gold standard” in the diagnosis of liver diseases. A pilot trial has shown pethidine may reduce anxiety and the need for post-procedural pain relief. The aim of this stu...

    Authors: Antony Pan, Mohammed Alansari, Ralf Lubcke, Martin Schlup, Merrilee Williams, Margaret Fraser, Sarah Buckingham and Michael Schultz
    Citation: BMC Gastroenterology 2015 15:33
  17. The presence of diabetes mellitus (DM) is associated with increased liver morbidity and mortality risk in patients with chronic hepatitis B (CHB). Aim of this study was to identify factors associated with type...

    Authors: Yi Shen, Jian Zhang, Hui Cai, Jian-Guo Shao, You-Yi Zhang, Yan-Mei Liu, Gang Qin and Yan Qin
    Citation: BMC Gastroenterology 2015 15:32
  18. Free perforation is the most severe and debilitating complication associated with Crohn’s disease (CD), and it usually requires emergency surgery. The aim of this study was to evaluate the incidence of free pe...

    Authors: Young Seok Doh, You Sun Kim, Song I Bae, Jong Pil Im, Jae Hee Cheon, Byong Duk Ye, Ji Won Kim, Young Sook Park, Ji Hyun Lee, Young-Ho Kim, Joo Sung Kim, Dong Soo Han and Won Ho Kim
    Citation: BMC Gastroenterology 2015 15:31
  19. To observe and compare the short term results and functional recovery of laparoscopic subtotal colectomy with antiperistaltic cecorectal anastomosis (LSCACRA) in the treatment of Adult slow transit constipatio...

    Authors: Dong Wei, Jian Cai, Yang Yang, Ting Zhao, Hui Zhang, Changshan Zhang, Yuanyao Zhang, Jianfeng Zhang and Fengbo Cai
    Citation: BMC Gastroenterology 2015 15:30
  20. Cystic echinococcosis (CE) is one of emerging zoonotic parasitic diseases throughout the world, having significant medical and economic importance in developing countries. The western and northwestern China is...

    Authors: Tiemin Zhang, Wei Zhao, Dong Yang, Daxun Piao, Shibo Huang, Yuanyuan Mi, Xianqi Zhao, Jianping Cao, Yujuan Shen, Weizhe Zhang and Aiqin Liu
    Citation: BMC Gastroenterology 2015 15:29
  21. Although most patients with autoimmune pancreatitis (AIP) respond favorably to prednisolone therapy, some individuals who later suffer from pancreatic calculi may require additional extracorporeal shock wave l...

    Authors: Masahiro Maruyama, Takayuki Watanabe, Keita Kanai, Takaya Oguchi, Jumpei Asano, Tetsuya Ito, Takashi Muraki, Hideaki Hamano, Norikazu Arakura, Takeshi Uehara and Shigeyuki Kawa
    Citation: BMC Gastroenterology 2015 15:28
  22. The cause of idiopathic pulmonary fibrosis (IPF) remains unknown, yet gastro-esophageal reflux disease (GERD) is highly prevalent in this population. GERD prevalence was studied, and esophageal function tests ...

    Authors: Feng Gao, Anthony Robert Hobson, Zhan Min Shang, Yan Xiang Pei, Yan Gao, Jian Xin Wang and Wan Nong Huang
    Citation: BMC Gastroenterology 2015 15:26
  23. Fatty liver disease (FLD) including non-alcoholic fatty liver disease (NAFLD), a rapidly emerging and widely recognized liver disease today, is regarded as a hepatic manifestation of metabolic syndrome. Helicobac...

    Authors: Kazuya Okushin, Yu Takahashi, Nobutake Yamamichi, Takeshi Shimamoto, Kenichiro Enooku, Hidetaka Fujinaga, Takeya Tsutsumi, Yoshizumi Shintani, Yoshiki Sakaguchi, Satoshi Ono, Shinya Kodashima, Mitsuhiro Fujishiro, Kyoji Moriya, Hiroshi Yotsuyanagi, Toru Mitsushima and Kazuhiko Koike
    Citation: BMC Gastroenterology 2015 15:25
  24. Systemic sclerosis (SSc) is a generalized disorder of unknown etiology affecting the connective tissue of the body. It affects the skin and various internal organs. Gastrointestinal tract involvement is seen i...

    Authors: Tasleem Arif, Qazi Masood, Jaswinder Singh and Iffat Hassan
    Citation: BMC Gastroenterology 2015 15:24
  25. Empiric triple treatments for Helicobacter pylori (H. pylori) are increasingly unsuccessful. We evaluated factors associated with failure of these treatments in the central region of Portugal.

    Authors: Nuno Almeida, Maria Manuel Donato, José Manuel Romãozinho, Cristina Luxo, Olga Cardoso, Maria Augusta Cipriano, Carol Marinho, Alexandra Fernandes, Carlos Calhau and Carlos Sofia
    Citation: BMC Gastroenterology 2015 15:23
  26. Non-alcoholic steatohepatitis (NASH) is associated with hepatic fibrogenesis. Despite well-known cholesterol-lowering action of statins, their mechanisms against NASH-mediated fibrogenesis remain unclear. This...

    Authors: Lee-Won Chong, Yi-Chao Hsu, Ting-Fang Lee, Yun Lin, Yung-Tsung Chiu, Kuo-Ching Yang, Jaw-Ching Wu and Yi-Tsau Huang
    Citation: BMC Gastroenterology 2015 15:22
  27. We have demonstrated previously that NFKB1 single nucleotide polymorphism (SNP) rs4648068 GG homozygote was associated with the increased risk of gastric cancer in Chinese Han population. In this study, we con...

    Authors: Ying Chen, Renquan Lu, Hui Zheng, Ran Xiao, Jingjing Feng, Hongling Wang, Xiang Gao and Lin Guo
    Citation: BMC Gastroenterology 2015 15:21
  28. Liver surgery in perihilar cholangiocarcinoma (PHC) is associated with high postoperative morbidity because the tumor typically causes biliary obstruction. Preoperative biliary drainage is used to create a saf...

    Authors: Jimme K Wiggers, Robert JS Coelen, Erik AJ Rauws, Otto M van Delden, Casper HJ van Eijck, Jeroen de Jonge, Robert J Porte, Carlijn I Buis, Cornelis HC Dejong, I Quintus Molenaar, Marc GH Besselink, Olivier RC Busch, Marcel GW Dijkgraaf and Thomas M van Gulik
    Citation: BMC Gastroenterology 2015 15:20
  29. Pancreatitis induced by hypertriglyceridemia (HTG) has gained much attention. However, very limited numbers of studies have focused on the clinical significance of TG elevation in non-HTG induced pancreatitis,...

    Authors: Long Cheng, Zhulin Luo, Ke Xiang, Jiandong Ren, Zhu Huang, Lijun Tang and Fuzhou Tian
    Citation: BMC Gastroenterology 2015 15:19
  30. Although numerous epidemiological studies on appendicitis have been conducted worldwide, only a few studies have paid attention to the effect of socioeconomic status on appendicitis, particularly studies focus...

    Authors: Kai-Biao Lin, Chien-Lung Chan, Nan-Ping Yang, Robert K Lai, Yuan-Hung Liu, Shun-Zhi Zhu and Ren-Hao Pan
    Citation: BMC Gastroenterology 2015 15:18
  31. Gastric epithelial dysplasia (GED) can be morphologically categorized into adenomatous and foveolar types. To date, there have been few studies on the clinical characteristics of GEDs according to the morpholo...

    Authors: Dong Hoon Baek, Gwang Ha Kim, Do Youn Park, Bong Eun Lee, Hye Kyung Jeon, Won Lim and Geun Am Song
    Citation: BMC Gastroenterology 2015 15:17
  32. Alpha-fetoprotein (AFP)-producing pancreatic neuroendocrine tumors (pNETs) are rare, and the few reported cases usually coexisted with other malignant components such as adenocarcinoma or hepatoid carcinoma. W...

    Authors: Xiang Zhu, Huijuan Yong, Li Zhang, Yonghui Huang, Jie Zheng, Cuiling Liu, Dianrong Xiu and Pan Zhang
    Citation: BMC Gastroenterology 2015 15:16
  33. Gastrointestinal endoscopy plays a crucial role in the diagnosis and management of gastrointestinal disorders. When endoscopy is indicated during pregnancy, concerns about the effects on pregnancy outcome ofte...

    Authors: Alison De Lima, Boris Galjart, Pieter HA Wisse, Wichor M Bramer and C Janneke van der Woude
    Citation: BMC Gastroenterology 2015 15:15
  34. Tofacitinib, a novel, oral Janus kinase inhibitor, demonstrated a dose-dependent efficacy for induction of clinical response and remission in patients with active ulcerative colitis (UC). The objective of the ...

    Authors: Julián Panés, Chinyu Su, Andrew G Bushmakin, Joseph C Cappelleri, Carla Mamolo and Paul Healey
    Citation: BMC Gastroenterology 2015 15:14
  35. Cross-sectional imaging techniques as magnetic resonance enterography (MRE) may offer additional information on transmural inflammation, stricturing and fistulising complications in Crohn’s disease (CD). The p...

    Authors: Feng Qi, Shen Jun, Qiao Yu Qi, Peng Jiang Chen, Geng Xiao Chuan, Zhu Jiong and Xu Jian Rong
    Citation: BMC Gastroenterology 2015 15:12
  36. Colonoscopy offers limited protection against right-sided colon cancer, a significant proportion of which arise from the serrated pathway of carcinogenesis. The aim of this study was to compare cap-assisted co...

    Authors: Fadi Rzouq, Neil Gupta, Sachin Wani, Prateek Sharma, Ajay Bansal and Amit Rastogi
    Citation: BMC Gastroenterology 2015 15:11
  37. Although poor sleep is common in numerous gastrointestinal diseases, data are scarce on the risk of poor sleep in celiac disease. The objective of this study was to estimate the risk of repeated use of hypnoti...

    Authors: Karl Mårild, Timothy I Morgenthaler, Virend K Somers, Suresh Kotagal, Joseph A Murray and Jonas F Ludvigsson
    Citation: BMC Gastroenterology 2015 15:10
  38. Environmental and genetic factors contribute to variation in irritable bowel syndrome (IBS), anxiety and depression. Comorbidity between these disorders is high. A previous investigation of our population-base...

    Authors: May-Bente Bengtson, Geir Aamodt, Morten H Vatn and Jennifer R Harris
    Citation: BMC Gastroenterology 2015 15:9
  39. Endoscopic biliary stenting (EBS) is one of the most important palliative treatments for biliary tract cancer. However, reflux cholangitis arising from bacterial adherence to the inner wall of the stent must b...

    Authors: Noritoshi Kobayashi, Seitaro Watanabe, Kunihiro Hosono, Kensuke Kubota, Atsushi Nakajima, Takashi Kaneko, Kazuya Sugimori, Motohiko Tokuhisa, Ayumu Goto, Ryutaro Mori, Koichi Taniguchi, Ryusei Matsuyama, Itaru Endo, Shin Maeda and Yasushi Ichikawa
    Citation: BMC Gastroenterology 2015 15:8
  40. Intra-tumor heterogeneity is a potential cause for failure of targeted therapy in gastric cancer, but the extent of heterogeneity of established (HER2) or potential (EGFR, CCND1) target genes and prognostic ge...

    Authors: Phillip Stahl, Carsten Seeschaaf, Patrick Lebok, Asad Kutup, Maximillian Bockhorn, Jakob R Izbicki, Carsten Bokemeyer, Ronald Simon, Guido Sauter and Andreas H Marx
    Citation: BMC Gastroenterology 2015 15:7
  41. In this study, we evaluated the technical feasibility of mucosal approximation of large ulcers via an endoscopic suturing system after endoscopic submucosal dissection (ESD), assessed the durability of these s...

    Authors: Masakuni Kobayashi, Kazuki Sumiyama, Yamato Ban, Akira Dobashi, Tomohiko Richard Ohya, Daisuke Aizawa, Shinichi Hirooka, Kiyokazu Nakajima and Hisao Tajiri
    Citation: BMC Gastroenterology 2015 15:5
  42. Celiac disease (CD) is a global health problem and its prevalence is underestimated, especially in Latin American populations. Our aim was to evaluate the clinical features, psychological factors, and health-r...

    Authors: Karen Lizzete Ramírez-Cervantes, José María Remes-Troche, María del Pilar Milke-García, Viridiana Romero and Luis F Uscanga
    Citation: BMC Gastroenterology 2015 15:4
  43. The prevalence of obesity has increased at alarming rates, particularly because of the increased consumption of high-fat diets (HFDs). The influence of HFDs on intrinsic innervation and the intestinal wall has...

    Authors: Angelica Soares, Evandro José Beraldi, Paulo Emílio Botura Ferreira, Roberto Barbosa Bazotte and Nilza Cristina Buttow
    Citation: BMC Gastroenterology 2015 15:3
  44. Esophageal stenosis following endoscopic submucosal dissection (ESD) is a serious adverse event that makes subsequent management more difficult.

    Authors: Hiroaki Takahashi, Yoshiaki Arimura, Satoshi Okahara, Junichi Kodaira, Kaku Hokari, Hiroyuki Tsukagoshi, Yasuhisa Shinomura and Masao Hosokawa
    Citation: BMC Gastroenterology 2015 15:1

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